Accutane Prices and Savings - Inside Rx.Accutane Prices - U.S. & International | localhost

Looking for:

Price comparison for accutane 

Click here

     

-

 

Objectives: The cost-effectiveness of systemic isotretinoin therapy in the treatment of moderate to severe acne was assessed in a comparative cost-minimisation analysis. The perspective taken was that of the funder of health care, and the resources used were funder charges as a proxy for costs.

Methodology: Statistical and epidemiological data as well as relevant costs from the previously reported meta-analysis and profiling study for acne therapy were used as the clinical basis for the construction of a cost-minimisation model. Additional costs were sourced from published pharmaceutical retail prices and professional rates. The South African treatment guidelines were used to define the frequencies associated with physician visits and pathology testing. Standard statistical methods were applied, as appropriate.

From the above, a modified Markov process was used to model the costs associated with the four comparator treatment regimens over a period of months. Suitable clinical and economic endpoints were defined so that comparison could be made between regimens.

Results: Assuming a relapse rate of For the stepped therapy of oral antibiotics followed by systemic isotretinoin, these break-even periods were 56 and 39 months, respectively. The cost per successfully treated patient receiving isotretinoin was R This compares well with the cost for those patients receiving chronic oral antibiotics, which after 5 years amounted to R10 per patient.

Sensitivity analyses proved these findings to be robust to variations in the isotretinoin relapse rate, and the cost of oral antibiotic therapy and the concomitant use of topical therapies.

Conclusion: From the cost-minimisation model it is clear that where systemic isotretinoin is clinically indicated, the sooner such therapy is initiated the more cost-effective the outcome will be. If isotretinoin is prescribed on diagnosis of moderate to severe acne, then the cost of treatment is significantly reduced in the long term when compared with standard chronic oral antibiotic therapy. Abstract Objectives: The cost-effectiveness of systemic isotretinoin therapy in the treatment of moderate to severe acne was assessed in a comparative cost-minimisation analysis.

    ❾-50%}