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Differin and finacea
We're building a better ClinicalTrials. Check it out and tell us what you think! Hide glossary Glossary Study record managers: refer to the Data Element Definitions if submitting registration or results information.
Search for terms. Save this study. Warning You have reached the maximum number of saved studies Listing a study does not mean it has been evaluated by the U. Federal Government. Read our disclaimer for details. Last Update Posted : July 8, Study Description. Detailed Description:. Drug Information available for: Azelaic acid Adapalene. FDA Resources. Arms and Interventions.
Outcome Measures. Secondary Outcome Measures : - Change of non-inflammatory, inflammatory and total lesions at all visits. Eligibility Criteria. Inclusion Criteria: Female subjects between 18 and 45 years of age, inclusive, in good general health.
Female Subjects of childbearing potential using effective contraceptional methods must have been taking the same type of birth control for at least 6 months prior to entering the study and must not change type of birth control during the study.
Subjects with visible microcomedones on the Cyanoacrylate strip taken on the forehead. Subjects must read and sign the approved Informed Consent Form and any local or national authorized requirements prior to any participation in the study. Subjects must be willing and capable of cooperating to the extent and degree required by the protocol including refraining from the use of cosmetics and ointments during the course of treatment. Subject must be able to follow all study procedures, attend all schedule visits, and complete the study successfully.
Exclusion Criteria: Female subjects who are pregnant, trying to become or willing to become pregnant, or who are lactating. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
All rights reserved. Use of this site constitutes acceptance of eHealthMe. Toggle navigation eHealth Me. Home Analysis. Adapalene vs. Finacea: side effect and effectiveness comparison - a phase IV clinical study Summary: We compare the side effects and drug effectiveness of Adapalene and Finacea. What is Adapalene? What is Finacea? Finacea: not at all : 3. Close Back.
Sign in. Join now. Follow us on:. Search PracticeUpdate Cancel. Improvement in acne severity and lesion counts was comparable between groups, but dryness and scaling were significantly lower in the AzA group compared with the AD group. AzA is noninferior to AD and may be tolerated better for treatment including maintenance treatment of adult acne. This abstract is available on the publisher's site. Access this abstract now.
❿Differin and Azelaic Acid for UK readers - Caroline Hirons
Azelaic Acid vs Adapalene in Treatment of Female Adult Acne | PracticeUpdate
Join now. Follow us on:. Search PracticeUpdate Cancel. Improvement in acne severity and lesion counts was comparable between groups, but dryness and scaling were significantly lower in the AzA group compared with the AD group. AzA is noninferior to AD and may be tolerated better for treatment including maintenance treatment of adult acne. This abstract is available on the publisher's site. Access this abstract now. METHODS A total of 55 women between 18 and 45 years with adult acne were included in this investigator-blind trial and randomized into three groups receiving AzA gel b.
Additional Info. Drug: differin 0. Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. We're building a better ClinicalTrials. Check it out and tell us what you think!
Hide glossary Glossary Study record managers: refer to the Data Element Definitions if submitting registration or results information. Search for terms. Save this study.
Warning You have reached the maximum number of saved studies Listing a study does not mean it has been evaluated by the U. Federal Government. Read our disclaimer for details. Last Update Posted : July 8, Study Description. Detailed Description:. Drug Information available for: Azelaic acid Adapalene.
FDA Resources. Arms and Interventions. Outcome Measures. Secondary Outcome Measures : - Change of non-inflammatory, inflammatory and total lesions at all visits. Eligibility Criteria. Inclusion Criteria: Female subjects between 18 and 45 years of age, inclusive, in good general health.
Female Subjects of childbearing potential using effective contraceptional methods must have been taking the same type of birth control for at least 6 months prior to entering the study and must not change type of birth control during the study. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect.
The use of the eHealthMe site and its content is at your own risk. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. All rights reserved. Use of this site constitutes acceptance of eHealthMe. Toggle navigation eHealth Me. Home Analysis. Adapalene vs.
Study record managers: refer to the Data Element Definitions if submitting registration or results information. Differin gel, containing adapalene 0. It has comedolytic and anti-inflammatory activities,and is equally effective and less irritant than other topical retinoids.
Adapalene has been shown to maintain therapeutic effect achieved after three months of monotherapy for further three months. Furthermore, its effect in maintenance therapy has been shown in several studies after initial combination with topical or systemic antimicrobials. Vehicle-controlled studies have verified that AzA exercises a significant and clinically relevant effect on both non-inflammatory and inflammatory acne lesions. In the treatment of moderate to severe acne, 20 percent AzA cream may be favorably combined with minocycline 90 percent good and excellent resultsand may contribute towards reducing recurrences following discontinuation of systemic therapy maintenance therapy with AzA cream.
Particular advantages of AzA therapy include its favorable safety and side effect profile. It is non-teratogenic, is not associated with systemic adverse events or photodynamic reactions, exhibits excellent local tolerability, and does not induce resistance in Propionibacterium acnes. This inclusion criterion corresponds to the clinical grades usually treated with topical anti-acne therapies. Acne lesion counting has been used widely in the evaluation of new acne treatments as a change in facial acne lesions counts over time in an individual patient could reflect a true change.
However, lesion counts are more valid in greater patient populations as planned in this study. Therefore, the lesion counts are defined as secondary efficacy criteria except during the maintenance phase for the population treated with azelaic acid.
As described before, microcomedones are considered as precursor lesion. Moreover, their counts are constantly reduced during acne treatment and precede the clinical relapse. Therefore, microcomedones counts will be used in this trial as a marker of maintenance of therapeutic effect achieved during initial treatment phase.
Drug: differin 0. Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. We're building a better ClinicalTrials. Check it out and tell us what you think!
Hide glossary Glossary Study record managers: refer to the Data Element Definitions if submitting registration or results information. Search for terms.
Save this study. Warning You have reached the maximum number of saved studies Listing a study does not mean it has been evaluated by the U. Federal Government. Read our disclaimer for details. Last Update Posted : July 8, Study Description.
Detailed Description:. Drug Information available for: Azelaic acid Adapalene. FDA Resources. Arms and Interventions. Outcome Measures. Secondary Outcome Measures : - Change of non-inflammatory, inflammatory and total lesions at all visits. Eligibility Criteria. Inclusion Criteria: Female subjects between 18 and 45 years of age, inclusive, in good general health. Female Subjects of childbearing potential using effective contraceptional methods must have been taking the same type of birth control for at least 6 months prior to entering the study and must not change type of birth control during the study.
Subjects with visible microcomedones on the Cyanoacrylate strip taken on the forehead. Subjects must read and sign the approved Informed Consent Form and any local or national authorized requirements prior to any participation in the study. Subjects must be willing and capable of cooperating to the extent and degree required by the protocol including refraining from the use of cosmetics and ointments during the course of treatment.
Subject must be able to follow all study procedures, attend all schedule visits, and complete the study successfully. Exclusion Criteria: Female subjects who are pregnant, trying to become or willing to become pregnant, or who are lactating. Subjects who have any clinically relevant finding at their screening physical examination or medical history such as severe systemic diseases or diseases of the facial skin other than acne vulgaris eg, acne conglobata, acne fulminans, secondary-acne or severe nodulocystic acne requiring treatment with oral isotretinoin.
Subjects who have a known hypersensitivity or previous allergic reaction to any of the active components of the study medication. Subjects who are using and not willing to refrain from the following other types of facial products: astringents, toners, abradants, facials, peels containing glycolic or other acids, masks, washes or soaps.
Subjects who have used topical corticosteroids on the face or systemic corticosteroids within the past 2 weeks. Subjects who have used topical antibiotics on the face or systemic antibiotics only penicillin allowed within the last 2 weeks.
Subjects who have used topical anti-acne medications within the past 2 weeks. Subjects who have used systemic retinoids within the past 6 months. Subjects who use medications that are reported to exacerbate acne Subjects who are using drugs known to be photosensitizers because of the possibility of increased phototoxicity. Subjects who have had a facial procedure performed by an esthetician, beautician, physician, nurse, or other practitioner, within the last 4 weeks.
Subjects who planned intensive UV exposure during study Subjects who participated in another investigational drug or device research study within 30 days of enrollment. Contacts and Locations.
Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials. More Information. National Library of Medicine U. National Institutes of Health U.
Department of Health and Human Services. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Acne Vulgaris. Drug: skinoren Drug: differin. Phase 4. Study Type :. Interventional Clinical Trial. Actual Enrollment :. Study Start Date :. Actual Primary Completion Date :. Actual Study Completion Date :. Active Comparator: Differin Gel 0. Drug: skinoren 12 weeks treatment, the following 24 months only observation Other Name: Generikum.
July 4, Key Record Dates.
localhost › › Drugs › Azelaic Acid. Finacea (azelaic acid 15% gel) works just as well as a topical retinoid (similar to Retin-A) called adapalene (Differin) for women with. Finacea is a prescription topical gel that contains 15% azelaic acid. It is FDA approved to treat redness (inflammation) and papules (raised. Boots offers Differin Cream (gentler than the gel) and 20% Azaleic Acid, while Superdrug offers Epiduo and Isotrex, among others. I'd personally. Differin and Finacea have different exfoliating properties so I would not add a glycolic acid for quite some time. Otherwise you risk increase. Contacts and Locations.Growing numbers of post-adolescent females are suffering from treatment-resistant or relapsing adult acne forms, therefore requiring the definition of safe and effective treatment options for this burdening disease. A total of 55 women between 18 and 45 years with adult acne were included in this investigator-blind trial and randomized into three groups receiving AzA gel b.
Parameters of efficacy, safety and patient-related factors were analysed. From week 12 to week 36, a mild relative increase in inflammatory lesions could be observed in all groups. Allergy Clin. Property Value Status. We have detected that you are using an Ad Blocker. PracticeUpdate is free to end users but we rely on advertising to fund our site. Please consider supporting PracticeUpdate by whitelisting us in your ad blocker. We have sent a message to the email address you have provided,.
If this email is not correct, please update your settings with your correct address. The email address you provided during registration, , does not appear to be valid. Please update your settings with a valid address before to continue using PracticeUpdate. Close Back. Sign in. Join now. Follow us on:. Search PracticeUpdate Cancel. Improvement in acne severity and lesion counts was comparable between groups, but dryness and scaling were significantly lower in the AzA group compared with the AD group.
AzA is noninferior to AD and may be tolerated better for treatment including maintenance treatment of adult acne. This abstract is available on the publisher's site. Access this abstract now. METHODS A total of 55 women between 18 and 45 years with adult acne were included in this investigator-blind trial and randomized into three groups receiving AzA gel b. Additional Info. National Library of Medicine. Become a PracticeUpdate member now.
Further Reading. Dermatology Dermatology.
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