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❾-50%}- Isotretinoin: The truth about side effects
When other treatment fails, this medication can diminish or clear severe acne and prevent new acne scars. Accutane is a brand name of isotretinoin that is no longer available. Whether you call it Accutane or isotretinoin, myths and misconceptions about this medication are common. This is especially when it comes to side effects. It's important to remember that all medications have potential side effects.
Pregnancy risks: If a person takes isotretinoin while pregnant, this medication can cause:. Prevent pregnancy risks: To get a prescription for isotretinoin, a patient who can become pregnant must take two pregnancy tests to make sure they're not pregnant. Patients who can get pregnant must also agree that while taking this medication, they will have a monthly pregnancy test and use two forms of birth control.
Treat dryness: Once you stop taking the medication, dryness will clear. Until then, you can get relief with moisturizer, lip balm, and artificial tears. For nosebleeds, apply petroleum jelly just inside your nose. This helps keep the tissue moist, which can prevent nosebleeds. Sun-sensitive skin: When you take isotretinoin, you may become extremely sensitive to the sun. This medication can make your skin more sensitive to the sun.
You can sunburn quickly and unexpectedly. Manage sun-sensitive skin: To protect your skin from the sun, dermatologists recommend that you Practice Safe Sun.
Your dermatologist may also give you other tips. Once you stop taking isotretinoin, this sensitivity will go away. Acne worsens: Because isotretinoin effectively treats so many people with severe acne, many people are surprised by this possible side effect. Worsening acne is a temporary side effect: When you start taking isotretinoin, acne can worsen for months before it begins to clear.
This happens with many other acne treatments. Can affect your eyesight, hair, muscles, or joints: While taking isotretinoin, you may develop:.
These side effects are temporary: When you stop taking isotretinoin, these side effects tend to go away. If you experience thinning hair, your hair should grow back. Other possible side effects: When taking isotretinoin, other concerning side effects may occur. These include:.
Increasing pressure on the brain, which can lead to problems with your eyesight, permanent loss of eyesight, and, in rare cases, death. While some people have reported the following serious side effects, we don't have enough evidence to know whether isotretinoin is linked to or can cause the following:. Dermatologists use findings from this research to help their patients decide whether to take isotretinoin and to watch their patients for signs of side effects.
Ask your pharmacist to recommend a painkiller. Talk to your doctor if the headaches last longer than a week or are severe. Light exercise should not be a problem, but cut down on or avoid intense exercise and physical activity as it may make joint or muscle pain worse, particularly in children and teenagers. Speak to a doctor or pharmacist if the advice on how to cope does not help and a side effect is still bothering you or does not go away.
Serious side effects are usually rare and happen in less than 1 in 1, people. Stop taking isotretinoin capsules and call a doctor or contact straight away if:. Go to In rare cases, it's possible to have a serious allergic reaction anaphylaxis to isotretinoin capsules. You could be having a serious allergic reaction and may need immediate treatment in hospital. These are not all the side effects of isotretinoin capsules. For a full list, see the leaflet inside your medicines packet.
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It may be prescribed for other uses. Some serious side effects have been reported from taking it. Isotretinoin Accutane is a vitamin A derivative known as a retinoid. Your body reacts to it similar to how it reacts to vitamin A. Because vitamin A can build up in your tissues, it can quickly become a problem. You should not take vitamin A supplements while taking this drug. Isotretinoin is available as a variety of brand names, including Absorica, Amnesteem, Claravis, Myorisan, and Sotret.
The original brand, Accutane, is no longer on the market. However, the drug is sometimes still referred to by this name. Since isotretinoin is designed to treat severe acne, it has a visible effect on the skin. The medication can be very effective in treating severe acne because it targets:. The dose of isotretinoin a doctor prescribes may be linked with the severity of the side effects you may experience.
People prescribed lower doses may not have any common side effects, while higher doses may result in more severe side effects, according to the American Osteopathic College of Dermatology. While taking isotretinoin, your skin may be more sensitive to the sun. Be sure to use sun protection and skin moisturizers when outdoors. Avoid using any type of indoor tanning device. However, a study found insufficient evidence to support this recommendation.
It may be best to speak with a doctor about any upcoming cosmetic procedures while taking isotretinoin. Isotretinoin may cause increased pressure in your brainwhich is a life threatening condition. Symptoms of increasing brain pressure can include:.
Gastrointestinal disorders have been reported as a serious side effect of taking this medication. These may include:. But recent studies have not been able to establish a causal relationship between isotretinoin and these gastrointestinal diseases.
Tell a doctor if you notice any concerning gastrointestinal symptoms while taking isotretinoin. An allergic reaction to medication can be life threatening.
If you experience these symptoms after taking medication, callcontact your local emergency services, or have someone take you to the nearest hospital. It is possible to develop an allergy after repeated exposure to a medication. People in their childbearing years should take a pregnancy test before starting this medication.
An effective form of birth control, plus a backup method, should be used. People should not get pregnant for 4 weeks after this medication is stopped. If you do get pregnant, stop taking the medication and talk with a doctor right away.
Taking isotretinoin during pregnancy can cause miscarriage, death of the fetus, or premature birth. It can also lead to severe birth defects such as:. It can also cause a buildup of fluid and pressure on the brain called hydrocephalus. Babies may be born with an underdeveloped brain and small head, which is called microcephaly.
This can lead to intellectual and developmental disabilities. People should not breastfeed while taking isotretinoin or for at least 8 days after their last dose. It is an FDA-approved restricted distribution program designed to tell people about the risks of birth defects and to prevent pregnancy while taking the drug.
While taking isotretinoin, your red and white blood cell counts may decrease. Symptoms may include feeling faint and having difficulty breathing. Isotretinoin can also build up in your bloodstream. You may develop problems with blood sugar and blood fat levels. Some cases of sexual dysfunction linked to long-term isotretinoin use have been reported, but more detailed studies are needed to better explain these results. Stop taking isotretinoin immediately and talk with a doctor if you experience any of the side effects or symptoms below.
They may potentially lead to longer-term problems, such as organ damage, if not addressed promptly. These symptoms can include:. Some people taking isotretinoin may go through mood changessuch as irritability or sadness.
The potential for serious mental health problems, including depression, psychosis, and suicidal thoughts, has been reported with isotretinoin. Warning signs may include:. Some conflicting research exists related to the mental health side effects of taking isotretinoin.
Newer research published in the Journal of the American Academy of Dermatology has not found evidence of an increased risk for depression linked to isotretinoin treatment for acne.
A study also suggests the use of isotretinoin in patients with acne was linked with improved depression symptoms. More research is needed to fully understand the relationship between isotretinoin use and mental health side effects. Most side effects from taking isotretinoin go away within a few days to a few weeks after treatment stops.
But side effects may persist longer even after treatment ends. If left untreated, these side effects could result in permanent problems. In some cases, these may include conditions such as scarring or vision loss. Because of the danger to pregnant people, it is not recommended to donate blood while taking this medication or for a full month after you have stopped taking it. Contact a doctor as soon as possible if your side effects continue for more than a few weeks after you stop taking isotretinoin.
Isotretinoin can do a good job of clearing up your skin, but there is the potential for side effects while taking the medication. Most side effects fade within a few weeks after you stop taking the medication. Some side effects are more serious and need immediate treatment. Have a detailed conversation with a doctor to explore the risks and benefits of taking isotretinoin. A healthcare team can also work with you to manage any side effects.
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Skin Care. Medically reviewed by Alisha D. What is isotretinoin Accutane? Common side effects of isotretinoin Accutane. Share on Pinterest Illustration by Alyssa Kiefer.
Serious side effects of isotretinoin Accutane. Allergic reaction Any medication can cause a serious allergic reaction. Symptoms can include: hives swelling of the mouth or face breathing problems or anaphylaxis An allergic reaction to medication can be life threatening. Birth defects caused by isotretinoin Accutane. Long-term side effects of isotretinoin Accutane.
Mental health side effects of isotretinoin Accutane. Side effects after stopping isotretinoin Accutane. How we vetted this article: Sources. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references.
Other skin problems, including rashes, and mild itching. Sore or dry mouth or throat. headache, back pain, joint. scaling, redness, burning. Other skin problems, including rashes, and mild itching. This content does not have an Arabic version.Isotretinoin Accutane is a medication that doctors prescribe to treat severe acne. It is a retinoid, which is a class of drugs similar to vitamin A. Accutane has a range of side effects, including severe ones. This article will examine some of the side effects of Accutane. Before taking Accutane, and at regular intervals afterward, people will undergo blood tests to check their liver and kidney function, as well as their levels of fats and cholesterol. People taking Accutane may also have increased sensitivity to UV light, so they should use sun protection and avoid direct sunlight as much as possible.
Current advice says that people taking Accutane should also avoid waxing or other carrying out cosmetic skin procedures while taking the drug and for 6 months afterward. This is to prevent scarring. However, one review found no evidence to support delaying cosmetic procedures after using Accutane or products containing isotretinoin. That said, people should only perform such procedures with the advice of an experienced physician.
People sometimes mention weight gain or weight loss when talking about Accutane. However, the FDA do not currently list weight change as a side effect of this drug. It is very important that anyone who is pregnant, who is planning to become pregnant, or who may become pregnant accidentally does not take Accutane.
These effects are severe and not unusual. Different countries have introduced various regulatory procedures to prevent fetal exposure to this medication, including asking people to use two contraception methods during and after retinoid treatment and to take regular pregnancy tests.
One analysis reported that although the number of pregnancies, miscarriages, and fetal defects in people taking isotretinoin has decreased since then, they do still happen. Accutane may also increase the levels of blood cholesterol and fats in the body. Undergoing regular blood tests allows doctors to monitor these.
Taking Accutane may lead to a reduction in the number of red and white blood cells. Anemia may affect more than 1 in 10 people taking Accutane. The following sections will discuss the potential long-term side effects of Accutane in more detail. Accutane does not appear to affect fertility.
However, scientists have found a link between Accutane and sexual side effects, such as:. These severe but rare side effects may also persist after a person stops taking Accutane, so follow-up care is essential.
This could lead to permanent sight loss and, in rare cases, death. Accutane may increase the levels of sugar in the blood and, rarely, lead to diabetes.
People may experience a loss of night vision sometimes permanently and other severe eye problems from taking Accutane. This medication can also make it hard to wear contact lenses, and this difficulty may continue after treatment. As well as the more common, minor skin side effects, people have reported severe skin conditions with the use of Accutane.
Some of the long-term side effects may persist after a person has stopped taking Accutane. These may even cause permanent problems, such as scarring, vision loss, or internal organ damage. Some people had sexual side effects appear or become significantly worse after they had stopped treatment, according to one review. Meanwhile, a study found an increased risk of suicide for up to 6 months after Accutane treatment had stopped. However, the risk of attempting suicide was higher before treatment started.
For this reason, it is not possible to confirm any additional risk due to Accutane. People who are about to take Accutane should talk to their doctor about any other medications or herbal supplements they take. Likewise, taking St. People taking Accutane should see a doctor if any of the minor side effects persist and are causing them difficulty.
If anyone notices these symptoms while taking Accutane, they should stop taking the medication immediately and call a doctor. Also, anyone who breaks a bone should tell the doctor treating them that they are taking Accutane.
Accutane is an effective treatment for severe acne, but it has some serious side effects, including mental health problems and risks associated with pregnancy. Anyone who is considering taking this medication should have a detailed conversation with their doctor about the risks and how to reduce them.
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Medical News Today. Health Conditions Discover Tools Connect. What are the side effects of Accutane? Side effects Long-term After stopping Interactions Seeing a doctor Summary Isotretinoin Accutane is a medication that doctors prescribe to treat severe acne. Side effects of Accutane. Share on Pinterest Accutane has several potential side effects. Long-term side effects.
Side effects after stopping the drug. When to see a doctor. How we vetted this article: Sources. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. We avoid using tertiary references. We link primary sources — including studies, scientific references, and statistics — within each article and also list them in the resources section at the bottom of our articles.
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