Levofloxacin: MedlinePlus Drug Information
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[Acute pancreatitis after treatment by levofloxacin and methylprednisolone].Levofloxacin (Oral Route) Before Using - Mayo Clinic |
Case of drug-induced bullous pemphigoid by levofloxacin.Levofloxacin/methylprednisolone interaction | SpringerLink
Take levofloxacin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. You should begin to feel better during the first few days of treatment with levofloxacin. If your symptoms do not improve or if they get worse, call your doctor. Take levofloxacin until you finish the prescription, even if you feel better.
If you stop taking levofloxacin too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics. Levofloxacin is also sometimes used to prevent or treat traveler's diarrhea. Talk to your doctor about the risks of using this medication for your condition.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule.
Do not take a double dose to make up for a missed one. Levofloxacin may cause problems with bones, joints, and tissues around joints in children. Levofloxacin should not normally be given to children younger than 18 years of age unless they have plague or have been exposed to plague or anthrax in the air.
If your doctor prescribes levofloxacin for your child, be sure to tell the doctor if your child has or has ever had joint-related problems. Call your doctor if your child develops joint problems, such as pain or swelling, while taking levofloxacin or after treatment with levofloxacin. Levofloxacin may cause other side effects.
Call your doctor if you have any unusual problems while taking this medication. Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture not in the bathroom.
It is important to keep all medication out of sight and reach of children as many containers such as weekly pill minders and those for eye drops, creams, patches, and inhalers are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location — one that is up and away and out of their sight and reach. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them.
However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program.
In case of overdose, call the poison control helpline at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to levofloxacin.
If you have diabetes, your doctor may ask you to check your blood sugar more often while taking levofloxacin. Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking levofloxacin. Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish taking levofloxacin, call your doctor.
It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital.
It is also important information to carry with you in case of emergencies. Generic alternatives may be available. Levofloxacin pronounced as lee voe flox' a sin. Why is this medication prescribed? How should this medicine be used? Other uses for this medicine What special precautions should I follow? What special dietary instructions should I follow? What should I do if I forget a dose? What side effects can this medication cause?
What should I know about storage and disposal of this medication? Brand names. Talk to your doctor about the risks of taking levofloxacin. Other uses for this medicine. Levofloxacin may be used in children 6 months of age and older to prevent anthrax infection after possible exposure, and to treat plague infection. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of levofloxacin in the elderly.
However, elderly patients are more likely to have age-related tendon disorders including tendon rupture and kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving levofloxacin. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur.
In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:.
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Levofloxacin is in a class of antibiotics called fluoroquinolones. It works by killing bacteria that cause infections.
Antibiotics such as levofloxacin will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment. Levofloxacin comes as a tablet and a solution liquid to take by mouth. It is usually taken once a day. The length of your treatment depends on the type of infection you have. Your doctor will tell you how long to take levofloxacin.
The tablet may be taken with or without food. The solution should be taken 1 hour before or 2 hours after eating. Take levofloxacin at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take levofloxacin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
You should begin to feel better during the first few days of treatment with levofloxacin. If your symptoms do not improve or if they get worse, call your doctor. Take levofloxacin until you finish the prescription, even if you feel better. If you stop taking levofloxacin too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics. Levofloxacin is also sometimes used to prevent or treat traveler's diarrhea. Talk to your doctor about the risks of using this medication for your condition.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. Take the missed dose as soon as you remember it.
However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one. Levofloxacin may cause problems with bones, joints, and tissues around joints in children.
Levofloxacin should not normally be given to children younger than 18 years of age unless they have plague or have been exposed to plague or anthrax in the air. If your doctor prescribes levofloxacin for your child, be sure to tell the doctor if your child has or has ever had joint-related problems.
Call your doctor if your child develops joint problems, such as pain or swelling, while taking levofloxacin or after treatment with levofloxacin. Levofloxacin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication. Keep this medication in the container it came in, tightly closed, and out of reach of children.
Store it at room temperature and away from excess heat and moisture not in the bathroom. It is important to keep all medication out of sight and reach of children as many containers such as weekly pill minders and those for eye drops, creams, patches, and inhalers are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location — one that is up and away and out of their sight and reach.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet.
Instead, the best way to dispose of your medication is through a medicine take-back program. In case of overdose, call the poison control helpline at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at Keep all appointments with your doctor and the laboratory.
Your doctor may order certain lab tests to check your body's response to levofloxacin. If you have diabetes, your doctor may ask you to check your blood sugar more often while taking levofloxacin. Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking levofloxacin. Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish taking levofloxacin, call your doctor.
It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
However, elderly patients are more likely to have age-related tendon disorders including tendon rupture and kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving levofloxacin. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below.
The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases.
If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur.
Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:. There is a problem with information submitted for this request. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID, plus expertise on managing health.
To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you. If you are a Mayo Clinic patient, this could include protected health information. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices.
You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. All rights reserved.
Taking levofloxacin increases the risk that you will develop tendinitis swelling of a fibrous tissue that connects a bone to a muscle or have a tendon rupture tearing of a fibrous tissue that connects a bone to a muscle during your treatment or for up to several months afterward. These problems may affect tendons in your shoulder, your hand, the back of your ankle, or in other parts of your body. Tendinitis or tendon rupture may happen to people of any age, but the risk is highest in people over 60 years of age.
Tell your doctor if you have or have ever had a kidney, heart, or lung transplant; kidney disease; a joint or tendon disorder such as rheumatoid arthritis a condition in which the body attacks its own joints, causing pain, swelling, and loss of function ; or if you participate in regular physical activity.
Tell your doctor and pharmacist if you are taking oral or injectable steroids such as dexamethasone, methylprednisolone Medrolor prednisone Rayos.
If you experience any of the following symptoms of tendinitis, stop taking levofloxacin, rest, and call your doctor immediately: pain, swelling, tenderness, stiffness, or difficulty in moving a muscle.
If you experience any of the following symptoms of tendon rupture, stop taking levofloxacin and get emergency medical treatment: hearing or feeling a snap or pop in a tendon area, bruising after an injury to a tendon area, or inability to move or bear weight on an affected area.
Taking levofloxacin may cause changes in sensation and nerve damage that may not go away even after you stop taking levofloxacin. This damage may occur soon after you begin taking levofloxacin. Tell your doctor if you have ever had peripheral neuropathy a type of nerve damage that causes tingling, numbness, and pain in the hands and feet.
If you experience any of the following symptoms, stop taking levofloxacin and call your doctor immediately: numbness, tingling, pain, burning, or weakness in the arms or legs; or a change in your ability to feel light touch, vibrations, pain, heat, or cold.
Taking levofloxacin may affect your brain or nervous system and cause serious side effects. This can occur after the first dose of levofloxacin. Tell your doctor if you have or have ever had seizures, epilepsy, cerebral arteriosclerosis narrowing of blood vessels in or near the brain that can lead to stroke or ministrokestroke, changed brain structure, or kidney disease.
If you experience any of the following symptoms, stop taking levofloxacin and call your doctor immediately: seizures; tremors; dizziness; lightheadedness; headaches that won't go away with or without blurred vision ; difficulty falling asleep or staying asleep; nightmares; not trusting others or feeling that others want to hurt you; hallucinations seeing things or hearing voices that do not exist ; thoughts or actions towards hurting or killing yourself; feeling restless, anxious, nervous, depressed, memory problems, or confused, or other changes in your mood or behavior.
Taking levofloxacin may worsen muscle weakness in people with myasthenia gravis a disorder of the nervous system that causes muscle weakness and cause severe difficulty breathing or death. Tell your doctor if you have myasthenia gravis. Your doctor may tell you not to take levofloxacin. If you have myasthenia gravis and your doctor tells you that you should take levofloxacin, call your doctor immediately if you experience muscle weakness or difficulty breathing during your treatment.
Your doctor or pharmacist will give you the manufacturer's patient information sheet Medication Guide when you begin treatment with levofloxacin. Read the information carefully and ask your doctor or pharmacist if you have any questions.
Levofloxacin is used to treat certain infections such as pneumonia, and kidney, prostate a male reproductive glandand skin infections. Levofloxacin may also be used to treat bronchitis, sinus infections, or urinary tract infections but should not be used for bronchitis and certain types of urinary tract infections if there are other treatment options available. Levofloxacin is in a class of antibiotics called fluoroquinolones.
It works by killing bacteria that cause infections. Antibiotics such as levofloxacin will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment. Levofloxacin comes as a tablet and a solution liquid to take by mouth. It is usually taken once a day. The length of your treatment depends on the type of infection you have.
Your doctor will tell you how long to take levofloxacin. The tablet may be taken with or without food. The solution should be taken 1 hour before or 2 hours after eating. Take levofloxacin at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take levofloxacin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
You should begin to feel better during the first few days of treatment with levofloxacin. If your symptoms do not improve or if they get worse, call your doctor. Take levofloxacin until you finish the prescription, even if you feel better. If you stop taking levofloxacin too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.
Levofloxacin is also sometimes used to prevent or treat traveler's diarrhea. Talk to your doctor about the risks of using this medication for your condition. This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule.
Do not take a double dose to make up for a missed one. Levofloxacin may cause problems with bones, joints, and tissues around joints in children. Levofloxacin should not normally be given to children younger than 18 years of age unless they have plague or have been exposed to plague or anthrax in the air. If your doctor prescribes levofloxacin for your child, be sure to tell the doctor if your child has or has ever had joint-related problems.
Call your doctor if your child develops joint problems, such as pain or swelling, while taking levofloxacin or after treatment with levofloxacin. Levofloxacin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture not in the bathroom. It is important to keep all medication out of sight and reach of children as many containers such as weekly pill minders and those for eye drops, creams, patches, and inhalers are not child-resistant and young children can open them easily.
To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location — one that is up and away and out of their sight and reach. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. In case of overdose, call the poison control helpline at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at Keep all appointments with your doctor and the laboratory.
Your doctor may order certain lab tests to check your body's response to levofloxacin. If you have diabetes, your doctor may ask you to check your blood sugar more often while taking levofloxacin. Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking levofloxacin. Do not let anyone else take your medication. Your prescription is probably not refillable.
If you still have symptoms of infection after you finish taking levofloxacin, call your doctor. It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital.
It is also important information to carry with you in case of emergencies. Generic alternatives may be available. Levofloxacin pronounced as lee voe flox' a sin. Why is this medication prescribed? How should this medicine be used? Other uses for this medicine What special precautions should I follow? What special dietary instructions should I follow? What should I do if I forget a dose? What side effects can this medication cause? What should I know about storage and disposal of this medication?
Brand names. Talk to your doctor about the risks of taking levofloxacin. Other uses for this medicine. What special precautions should I follow? Before taking levofloxacin, tell your doctor and pharmacist if you are allergic or have had a severe reaction to levofloxacin; any other quinolone or fluoroquinolone antibiotic such as ciprofloxacin Ciprodelafloxacin Baxdelagemifloxacin Factivemoxifloxacin Aveloxand ofloxacin, or any other medications, or if you are allergic to any of the ingredients in levofloxacin preparations.
Ask your pharmacist or check the Medication Guide for a list of the ingredients. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: anticoagulants 'blood thinners' such as warfarin Coumadin, Jantoven ; certain antidepressants; antipsychotics medications to treat mental illness ; diuretics 'water pills' ; insulin or other medications to treat diabetes such as chlorpropamide, glimepiride Amaryl, in Duetactglipizide Glucotrolglyburide DiaBetatolazamide, and tolbutamide; certain medications for irregular heartbeat such as amiodarone Nexterone, Paceroneprocainamide, quinidine in Nuedextaand sotalol Betapace, Betapace AF, Sorine, Sotylize ; nonsteroidal anti-inflammatory drugs NSAIDs such as ibuprofen Advil, Motrin, others and naproxen Aleve, Naprosyn, others ; or theophylline Elixophyllin, Theo, Uniphyl, others.
Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Tell your doctor if you have or ever have had a slow or irregular heartbeat, a recent heart attack, an aortic aneurysm swelling of the large artery that carries blood from the heart to the bodyhigh blood pressure, peripheral vascular disease poor circulation in the blood vesselsMarfan syndrome a genetic condition that can affect the heart, eyes, blood vessels and bonesEhlers-Danlos syndrome a genetic condition that can affect skin, joints, or blood vesselsor if you have a low level of potassium or magnesium in your blood.
Also tell your doctor if you have or have ever had diabetes or problems with low blood sugar or liver disease. If you become pregnant while taking levofloxacin, call your doctor. Levofloxacin may make your skin sensitive to sunlight or ultraviolet light. If your skin becomes reddened, swollen, or blistered, like a bad sunburn, call your doctor. Make sure you drink plenty of water or other fluids every day while you are taking levofloxacin. Levofloxacin may cause side effects.
Talk to your doctor about the risks of taking levofloxacin or giving levofloxacin to your child. What other information should I know? Browse Drugs and Medicines.
A Major Drug Interaction exists between levofloxacin and prednisone. View detailed information regarding this drug interaction. The woman received levofloxacin mg/day for 2 weeks and tapered doses of methylprednisolone (16 to 8 mg/day) for 12 days. [Acute pancreatitis after treatment by levofloxacin and methylprednisolone]. Gastroenterol Clin Biol. Oct;25(10) [Article in French]. Levofloxacin: learn about side effects, dosage, steroids such as dexamethasone, methylprednisolone (Medrol), or prednisone (Rayos). Levofloxacin may be used in children 6 months of age and older to prevent Methadone; Methylprednisolone; Metronidazole; Mifepristone. Tell your doctor if you have or have ever had a kidney, heart, or lung transplant; kidney disease; a joint or tendon disorder such as rheumatoid arthritis a condition in which the body attacks its own joints, causing pain, swelling, and loss of function ; or if you participate in regular physical activity.Drug information provided by: IBM Micromedex. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:. Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals.
For non-prescription products, read the label or package ingredients carefully. Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of levofloxacin in children.
However, because of this medicine's toxicity, it should be used with caution, after other alternatives have been considered or found ineffective. Levofloxacin may be used in children 6 months of age and older to prevent anthrax infection after possible exposure, and to treat plague infection. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of levofloxacin in the elderly.
However, elderly patients are more likely to have age-related tendon disorders including tendon rupture and kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving levofloxacin.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur.
In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases.
If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:. There is a problem with information submitted for this request. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID, plus expertise on managing health.
To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you. If you are a Mayo Clinic patient, this could include protected health information. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices.
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