Long term effects of differin gel.Differin (Adapalene Topical)
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Long term effects of differin gel. Long-term safety and efficacy study of adapalene 0.3% gel
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❿Frequently Asked Questions | Differin Gel - User Reviews & Rating
Adapalene is a medicine similar to vitamin A. It helps the skin renew itself. Adapalene topical for use on the skin is used to treat severe acne in people who are at least 12 years old. Adapalene topical may also be used for purposes not listed in this medication guide. Ask a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions. It is not known whether adapalene passes into breast milk or if it could harm a nursing baby.
Do not use this medicine without a doctor's advice if you are breast-feeding a baby. It is not known whether adapalene will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.
Adapalene is not approved for use by anyone younger than 12 years old. Get emergency medical help if you have signs of an allergic reaction : hives, itching; chest pain, difficult breathing; swelling of your face, lips, tongue, or throat. Some side effects may occur during the first 4 weeks of using this medicine. These side effects should become less noticeable with continued use. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Avoid exposure to sunlight or tanning beds. Adapalene can make you sunburn more easily. Wear protective clothing and use sunscreen SPF 30 or higher when you are outdoors.
Avoid using other skin medications that contain sulfur, resorcinol, or salicylic acid common in topical acne medications or skin cleansers. Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime. Use Differin Adapalene Topical exactly as directed on the label, or as prescribed by your doctor.
Do not use in larger or smaller amounts or for longer than recommended. Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger amounts or for longer than recommended.
Using adapalene topical in larger amounts than recommended will not make it work faster, and may cause unpleasant side effects. Clean your skin with a mild non-medicated skin cleanser before applying the medicine. Pat the skin dry with a clean towel. Apply a thin layer to the entire face or other affected skin areas. Avoid applying the medicine to the creases of your nose, or on your lips. Do not apply to open wounds or on sunburned, windburned, dry, chapped, or irritated skin.
Do not apply any other skin products unless your doctor has told you to. You may use a skin moisturizer if your skin becomes dry while using adapalene. Avoid creams or lotions that contain alpha hydroxy or glycolic acids.
It may take several weeks before your acne improves, and it may get slightly worse for a short time when you first start using adapalene. Keep using the medication as directed, even if you think it is not working. Call your doctor if skin symptoms do not begin to improve within 8 to 12 weeks of using this medicine. Do not use adapalene topical to treat any condition that has not been checked by your doctor.
Apply the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not apply extra medicine to make up the missed dose. Health Conditions A-Z.
Health Tools. See All. DailyOM Courses. Differin Adapalene Topical. Generic Name: Adapalene topical. Reviewed: June 23, You should not use this medicine if you are allergic to adapalene. Side Effects. Stop using this medicine and call your doctor at once if you have: skin redness, stinging, burning, or peeling after sun exposure. Common side effects may include: dry, red, or scaly skin; feeling of warmth and mild stinging or burning; peeling skin; or skin pain. Based on FDA pregnancy categories.
Do not take by mouth. Adapalene is for use only on the skin. Adapalene topical is usually applied once daily in the evening. Wash your hands before applying this medicine.
Avoid getting this medicine in your eyes, nose, or mouth. Store at room temperature away from moisture and heat. Do not freeze. If you think you or someone else may have overdosed on: Differin Adapalene Topicalcall your doctor or the Poison Control center.
If someone collapses or isn't breathing after taking Differin Adapalene Topicalcall Medical Disclaimer Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. The information within all other sections is proprietary to Everyday Health. Read more.
❾-50%}Long term effects of differin gel.Differin® frequently asked questions
Do not use this medicine without a doctor's advice if you are breast-feeding a baby. It is not known whether adapalene will harm an unborn baby.
Do not use this medicine without a doctor's advice if you are pregnant. Adapalene is not approved for use by anyone younger than 12 years old. Get emergency medical help if you have signs of an allergic reaction : hives, itching; chest pain, difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during the first 4 weeks of using this medicine. These side effects should become less noticeable with continued use. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Avoid exposure to sunlight or tanning beds. Adapalene can make you sunburn more easily.
Wear protective clothing and use sunscreen SPF 30 or higher when you are outdoors. Avoid using other skin medications that contain sulfur, resorcinol, or salicylic acid common in topical acne medications or skin cleansers. Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime.
Use Differin Adapalene Topical exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger amounts or for longer than recommended. Using adapalene topical in larger amounts than recommended will not make it work faster, and may cause unpleasant side effects. Clean your skin with a mild non-medicated skin cleanser before applying the medicine.
Pat the skin dry with a clean towel. Do not use wax to remove unwanted hair in areas where the product has been applied. When possible, limit sun exposure, including light from tanning beds. When going outdoors, use sunscreen as labeled.
Yes, you can shave. A moisturizer may be used to help alleviate dryness. Differin Gel is approved for use in people 12 years and older with mild-to-moderate acne. If you have severe acne, talk to your doctor or visit acne. Differin Gel is a safe and effective treatment. Your long-term solution to clear and prevent acne. Get prescription strength without a prescription. Differin is different than what you're used to. Understand the process that makes it work. Knowledge, as they say, is power.
Learn acne types, causes and best ways to deal. Learn how the active ingredient in Differin Gel works differently to clear and prevent acne. Home Learn FAQ. How long has Differin Gel been on the market? What makes Differin Gel unique from other options currently available?
Is Differin Gel dermatologist developed and tested? Is there still a prescription version of Differin Gel? What are retinoids, and why are they important in clearing acne? Are all retinoids the same? Benefits include: Continually renews skin cells to help prevent pores from clogging Acting as an anti-inflammatory agent to reduce redness and swelling at the source Restoring skin tone and texture by clearing acne.
What is the difference between retinoid and retinol? What is the percentage of retinoid ingredient found in Differin Gel? How are retinoids different?
Adapalene vs. How long does Differin Gel take to work? Are there any side effects? What is retinization? When is irritation most likely to occur? If I experience irritation or signs of retinization , should I discontinue use?
During the first 3 weeks you are using adapalene, your acne may seem to get worse before it gets better. Full improvement should be seen within 12 weeks, especially if you use the medicine every day. You should not stop using adapalene if your acne seems worse at first, unless irritation or other symptoms become severe. Check with your doctor if your acne does not improve within 8 to 12 weeks.
Do not apply any topical product to the same area where you are using adapalene, unless otherwise directed by your doctor. If applied to the same area treated with adapalene, the following products may cause mild to severe irritation of the skin:. Your doctor may ask you to use other topical products, such as benzoyl peroxide, clindamycin, or erythromycin, during your treatment with adapalene. Applying the products at different times of the day will lessen the chance of causing skin irritation.
If your skin becomes too dry or red at any time, discuss with your doctor whether you should continue using adapalene. Applying creams, lotions, or moisturizers as needed helps lessen these skin problems. During treatment with this medicine, avoid getting too much sun on treated areas and do not use sunlamps.
Since your skin may be more prone to sunburn or skin irritation, use sunscreen or sunblocking lotions regularly with a sun protection factor SPF of 15 or more. Wear protective clothing against sun, wind, and cold weather. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:.
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects.
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Differin contains the only full prescription fighting retinoid available over the counter: adapalene. Differin Gel is dermatologist-developed, and its active ingredient — adapalene — has been prescribed to over 40 million people globally for more than 20 years. It was approved by the FDA for over-the-counter use without a prescription in Yes, Differin Gel is dermatologist developed and includes a dermatologist-recommended retinoid.
The AAD is the largest organization of dermatologists over 19, worldwide who provide public education about dermatology and dermatologic health. Yes, Differin Gel adapalene 0. For more than 20 years, doctors have prescribed the retinoid found in Differin Gel to over 40 million people globally. Differin Gel adapalene 0.
Other products containing adapalene are still available with a prescription. Topical retinoids, like Differin Gel, play a crucial role in the treatment of acne. Instudies linked abnormal cell turnover to vitamin A deficiencies. Retinoids have vitamin A activity and help regulate that turnover to make sure your skin goes through the right process, creating a healthier environment for skin.
Regulating skin cell turnover to a normal rate helps to keep the pores from clogging and target acne before it even starts. Through the years, researchers developed different forms of retinoids, which have become the basis for many prescription acne medications.
No, not all retinoids are created equal. There are currently three retinoids in use for topical acne medications — adapalene over the counter and prescriptiontretinoin and tazarotene.
Differin Gel uses adapalene, an ingredient designed with improved tolerability in mind, resulting in less redness and skin irritation. Adapalene has shown in studies to have superior tolerability compared to other prescription retinoid products not containing adapalene. Adapalene is also the first multi-benefit retinoid acne ingredient available over the counter, without a prescription.
Benefits include:. Retinol is a type of retinoid found in many cosmetic products. Differin Gel is the only OTC acne treatment to contain a prescription-strength retinoid. This powerful medication contains 0. Differin Gel clears redness and inflammation associated with acne and helps prevent pimples, blackheads and clogged pores before they occur. Differin Gel starts working immediately, and results may be seen in as little as two weeks.
Differin Gel has superior tolerability compared to other retinoid acne formulations not containing adapalene. These symptoms usually peak at the 2- to 4-week mark before subsiding. Not everyone will experience these side effects, and in clinical studies, average scores were less than mild. Retinization is the adjustment period in which the skin becomes acclimated with the retinoid. Irritation usually lessens after four weeks of continued, once-daily use.
This simply means Differin Gel is still working under the surface of the skin without causing any irritation. Differin Soothing Moisturizer works to help relieve the dryness associated with retinization. Avoid products containing salicylic acid, alpha hydroxy acid or glycolic acid, which may dry out your skin and worsen irritation.
Absolutely not. Use of Differin Gel should not be discontinued, but be sure to always use it just once daily. Try a gentle, non-comedogenic moisturizer, like Differin Soothing Moisturizerto help manage irritation.
The early skin irritation that sometimes occurs when using Differin Gel is known as retinization, which is the adjustment period when your skin adapts to the retinoid. Using a gentle cleanser and moisturizer may help decrease dryness and other signs of irritation.
If you experience prolonged symptoms, or if irritation becomes severe overly bothersomestop use and consult your physician before using the product again.
Irritation may occur if using more than one topical acne product at a time. Avoid products containing harsh chemicals, salicylic acid, alpha hydroxy acid or glycolic acid, which may dry out skin and worsen irritation. Differin Gel should be used only once daily and integrated as an important step into your morning or evening skincare routine. Try to apply the product at the same time each day.
For best results, first wash skin with a mild non-irritatingnon-drying cleanser; apply a thin layer of Differin Gel to clean, dry skin full face ; and follow treatment with a moisturizer.
If Differin Gel is used during the day, allow it to dry before applying sunscreen. Differin Gel should not be used more than once a day. Applying more than directed will not provide faster or better results. Differin Gel is different. For example, if you get acne on the face, Differin Gel should be applied to the entire face.
Differin Gel should not be used in conjunction with products containing alpha hydroxy, salicylic or glycolic acids, which may worsen irritation. Do not use wax to remove unwanted hair in areas where the product has been applied. When possible, limit sun exposure, including light from tanning beds. When going outdoors, use sunscreen as labeled. Yes, you can shave. A moisturizer may be used to help alleviate dryness.
Differin Gel is approved for use in people 12 years and older with mild-to-moderate acne. If you have severe acne, talk to your doctor or visit acne.
Differin Gel is a safe and effective treatment. Your long-term solution to clear and prevent acne. Get prescription strength without a prescription. Differin is different than what you're used to. Understand the process that makes it work. Knowledge, as they say, is power. Learn acne types, causes and best ways to deal. Learn how the active ingredient in Differin Gel works differently to clear and prevent acne.
Home Learn FAQ. How long has Differin Gel been on the market? What makes Differin Gel unique from other options currently available? Is Differin Gel dermatologist developed and tested? Is there still a prescription version of Differin Gel? What are retinoids, and why are they important in clearing acne? Are all retinoids the same? Benefits include: Continually renews skin cells to help prevent pores from clogging Acting as an anti-inflammatory agent to reduce redness and swelling at the source Restoring skin tone and texture by clearing acne.
What is the difference between retinoid and retinol? What is the percentage of retinoid ingredient found in Differin Gel?
How are retinoids different? Adapalene vs. How long does Differin Gel take to work? Are there any side effects? What is retinization? When is irritation most likely to occur? If I experience irritation or signs of retinizationshould I discontinue use? What can I do to minimize skin irritation?
How does Differin Gel look and feel? How often should I use Differin Gel? Can I use Differin Gel as a spot treatment? Why should Differin Gel be applied to the entire face? Can I stop using Differin Gel once my acne clears up?
Is it safe to shave while using Differin Gel with adapalene? Who should use Differin Gel? Is it okay for pregnant women to use Differin Gel? Shop Now. See Now. You May Also Like. We only send good stuff. Be the first to know about new products, discounts and skin health news. Sign Up.
Common side effects of Differin Gel include a brief sensation of warmth, stinging, tingling, or irritation immediately after applying the medication. Skin. Skin redness, dryness, itching, scaling, mild burning, or worsening of acne may occur during the first weeks of using the medication. These effects usually. Treatment-related, dermatologic adverse events were experienced by 21% of subjects and dry skin, skin discomfort, and scaling were reported by %, % and. See the frequently asked questions about Differin Gel (adapalene %) and How long has Differin Gel been on the market? Are there any side effects? Common side effects of Differin Gel include a brief sensation of warmth, stinging, tingling, or irritation immediately after applying the medication. Skin. Differin Gel is a safe and effective treatment. There are currently three retinoids in use for topical acne medications — adapalene over the counter and prescriptiontretinoin and tazarotene. Avoid creams or lotions that contain alpha hydroxy or glycolic acids. We only send good stuff. To help clear up your acne completely, it is very important that you keep using this medicine for the full time of treatmenteven if your symptoms begin to clear up after a short time. Understand the process that makes it work. Avoid applying the medicine to the creases of your nose, or on your lips.Drug information provided by: IBM Micromedex. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:. Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines.
Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Studies of this medicine have been done only in adult patients, and there is no specific information comparing use of adapalene in children up to 12 years of age with use in other age groups.
In teenagers, adapalene is not expected to cause different side effects or problems than it does in adults. Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of adapalene in the elderly with use in other age groups. Older adults are not likely to develop acne.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary.
Tell your healthcare professional if you are taking any other prescription or nonprescription over-the-counter [OTC] medicine. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur.
Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. The presence of other medical problems may affect the use of this medicine.
Make sure you tell your doctor if you have any other medical problems, especially:. It is very important that you use this medicine only as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause irritation of the skin. Do not use this medicine in or around the eyes, lips, or inside of the nose.
Spread the medicine away from these areas when applying. If the medicine accidently gets on these areas, wash with water at once. Apply the medicine to clean, dry areas of the skin affected by acne. Rub in gently and well. Wash your hands afterwards to remove any medicine that may remain on them. To help clear up your acne completely, it is very important that you keep using this medicine for the full time of treatment , even if your symptoms begin to clear up after a short time.
If you stop using this medicine too soon, your acne may return or get worse. The dose of this medicine will be different for different patients.
Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
During the first 3 weeks you are using adapalene, your acne may seem to get worse before it gets better. Full improvement should be seen within 12 weeks, especially if you use the medicine every day. You should not stop using adapalene if your acne seems worse at first, unless irritation or other symptoms become severe. Check with your doctor if your acne does not improve within 8 to 12 weeks.
Do not apply any topical product to the same area where you are using adapalene, unless otherwise directed by your doctor. If applied to the same area treated with adapalene, the following products may cause mild to severe irritation of the skin:. Your doctor may ask you to use other topical products, such as benzoyl peroxide, clindamycin, or erythromycin, during your treatment with adapalene.
Applying the products at different times of the day will lessen the chance of causing skin irritation. If your skin becomes too dry or red at any time, discuss with your doctor whether you should continue using adapalene. Applying creams, lotions, or moisturizers as needed helps lessen these skin problems. During treatment with this medicine, avoid getting too much sun on treated areas and do not use sunlamps. Since your skin may be more prone to sunburn or skin irritation, use sunscreen or sunblocking lotions regularly with a sun protection factor SPF of 15 or more.
Wear protective clothing against sun, wind, and cold weather. Along with its needed effects, a medicine may cause some unwanted effects.
Although not all of these side effects may occur, if they do occur they may need medical attention. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:.
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission.
Mayo Clinic does not endorse any of the third party products and services advertised. A single copy of these materials may be reprinted for noncommercial personal use only.
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