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Omeprazole (Oral Route) Precautions - Mayo Clinic - Before Using

I could not live a normal life without Predinisone. Once again good luck on your journey. Smile on my face working my way down the road. If you have a history of ulcers you should NOT have been put on alendronic acid - it is an explicit contraindication, particularly if it is in the last year or so, but I wouldn't accept being given it at all under the circumstances.

Join this discussion or start a new one? We want the forums to be a useful resource for our users but it is important to remember that the forums are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters.

Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the forums is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms. New discussion Reply. Rimmy mary EileenH mary Is Zantac an H2 inhibator? Michdonn amkoffee. Hi Mary I was prescribed Omeprazole. Michdonn mary Anhaga mary Michdonn Anhaga. I am one been on Omeprazole for years now.

I do not seem to have any problems with it, so far! EileenH Michdonn. Michdonn EileenH. Thanks, keep smiling! I have been on pred for a year and half, present dosage 6 mg. Recently, old ulcers, unknown to me, bled, caused by a blood thinner used duriing a knee replacement.

I was treated with two medications for a month beginningi in the hospital. A few months later, I was given mg Ranitidine 2 xs a day and developed hives after three pils. I was switched to 20 mg Omeprazole Prilosec 1 x a day for the remainder of the month. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. Blood, urine, and other laboratory tests may be needed to check for unwanted effects. If your or your child's condition does not improve, or if it becomes worse, check with your doctor.

You may need a lower dose of this medicine to treat erosive esophagitis. Using these medicines together may cause unwanted side effects. This medicine is sometimes given together with other medicines to treat ulcers. Be sure you understand about the risks and proper use of any other medicine your doctor gives you or your child together with omeprazole. Omeprazole may cause a serious type of allergic reaction when used in patients with conditions treated with antibiotics.

Call your doctor right away if you or your child has itching, trouble breathing or swallowing, or any swelling of your hands, face, or mouth. Check with your doctor right away if you or your child has a change in frequency of urination or amount of urine, blood in the urine, fever, joint pain, loss of appetite, skin rash, swelling of the body, feet, or ankles, unusual tiredness or weakness, or unusual weight gain after receiving this medicine.

These could be symptoms of a serious kidney problem called acute tubulointerstitial nephritis. Taking this medicine for a long time may make it harder for your body to absorb vitamin B Tell your doctor if you have concerns about vitamin B12 deficiency.

Serious stomach conditions may occur while taking this medicine alone or together with antibiotics. Check with your doctor immediately if you or your child has stomach cramps, bloated feeling, watery and severe diarrhea which may also be bloody sometimes, fever, nausea or vomiting, or unusual tiredness or weakness.

This medicine may increase your risk of having fractures of the hip, wrist, and spine. This is more likely if you are 50 years of age and older, if you receive high doses of this medicine, or use it for one year or more.

Call your doctor right away if you have severe bone pain or are unable to walk or sit normally. This medicine may cause serious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, and drug reaction with eosinophilia and systemic symptoms DRESS. Check with your doctor right away if you have black, tarry stools, blistering, peeling, or loosening of the skin, chest pain, chills, cough, diarrhea, itching, joint or muscle pain, painful or difficult urination, red irritated eyes, red skin lesions, often with a purple center, sore throat, sores, ulcers, or white spots in the mouth or on the lips, swollen glands, unusual bleeding or bruising, or unusual tiredness or weakness.

This medicine may cause hypomagnesemia low magnesium in the blood. Check with your doctor right away if you have convulsions seizures , fast, racing, or uneven heartbeat, muscle spasms tetany , tremors, or unusual tiredness or weakness. Cutaneous or systemic lupus erythematosus may occur or get worse in patients receiving a PPI.

Call your doctor right away if you have joint pain or a skin rash on your cheeks or arms that gets worse when exposed to the sun. This medicine may increase your risk for fundic gland polyps abnormal tissue growth in the upper part of your stomach.

This is more likely if you are receiving this medicine for more than 1 year. Talk to your doctor if you have concerns. Do not stop taking this medicine without first checking with your doctor, or unless told to do so by your doctor. Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before you have medical tests.

Do not take other medicines unless they have been discussed with your doctor. John's wort or vitamin supplements. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. It may even be prescribed to some patients that have these symptoms!

You may not, individually, be 'tolerating' either the Omeprazole, the steroid, or any other medication you might have been prescribed alongwith. I have taken steroids for anaphylaxsis and my son is on them for NS. I can tolerate high doses without reflux meds for atleast 2 weeks but he can't. I guess it is just an individual response. However if ur treatment plan requires you to take the steroids for a long period then I would advise that u stay on either Omeprazole or an alternative.

Sorry to hear you're having trouble with those meds. I take both of them every day and have never had a problem, other than that the prednisone ,makes my sugar go high, so I'm being weaned off it. However, that information will still be included in details such as numbers of replies.

Oops, something went wrong. Join Inspire Create a Post. Taking omeprazole with Prednisone? Mrkewl98 Inactive.

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Prednisolone and Omeprazole: Hi everyone I hope you - PMRGCAuk.

Hi folks. I had a question. I started Prednisone a few weeks back and the doc prescribed me Omeprazole as well. When I take that stuff, I have the worst stomache issues ever, cramps, bloating, and more.

Do I NEED to take the omeprazole with the prednisone or can people take prednisone without the acid medication? Well I was put on Omeprazole for a while to deal with the horrible intense acid-reflux and heartburn i was getting from my dose of pred Because steroids in this case, prednisolone can cause gastritis, and several other stomach-related adverse effects, doctors often prescribe anti-acid medication such as Omeprazole alongwith.

Omeprazole, normally, does not cause the symptoms you report. It may even be prescribed to some patients that have these symptoms! You may not, individually, be 'tolerating' either the Omeprazole, the steroid, or any other medication you might have been prescribed alongwith.

I have taken steroids for anaphylaxsis and my son is on them for NS. I can tolerate high doses without reflux meds for atleast 2 weeks but he can't. I guess it is just an individual response. However if ur treatment plan requires you to take the steroids for a long period then I would advise that u stay on either Omeprazole or an alternative. Sorry to hear you're having trouble with those meds.

I take both of them every day and have never had a problem, other than that the prednisone ,makes my sugar go high, so I'm being weaned off it.

However, that information will still be included in details such as numbers of replies. Oops, something went wrong. Join Inspire Create a Post. Taking omeprazole with Prednisone? Mrkewl98 Inactive. Sign in or join to bookmark. Thank you. React Sign in or join to react. Viewing as. Sort by. This discussion has been closed to comments. Please start a new post. Dear Friend, Because steroids in this case, prednisolone can cause gastritis, and several other stomach-related adverse effects, doctors often prescribe anti-acid medication such as Omeprazole alongwith.

In your case: 1. You need to talk to your doctor again; ask for substitutes for Omeprazole. There are a few. Desianne Inactive. Delete Reply. Note Required. Cancel Confirm. Read carefully Block Member. Are you sure you want to block this member? Cancel Block. Add as friend. This is a snackbar.

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Taking omeprazole with Prednisone? - Nephrotic syndrome and FSGS.

This is a decision you and your doctor will make.

Klinefelters sufferers get small breasts! She referred me to the Diabetes specialist at Heath Road who was also an Endocrinologist, and he took one look at my distorted facial features, very long legs and arms and compacted rib cage and said I think I know what's causing the problem but I have to do special blood tests to confirm the diagnosis.

I can make you feel better and stop the fractures but the treatment will go on for the rest of your life. There are a more horrors but I will stop there. So, I'd been on omeprazole for years before I started Prednisolone and have never had any problems.

I'm on 8. Bear in mind that I am different to most of the male population, I just have had a similar combination of the same drugs that you are asking about. Thank you for your reply Colin.

So sorry to hear about your diagnosis. Sounds as though you have had a lot to contend with over the years. Looks like not everyone suffers long term effects. I just hate being on medication that I might not need, even if no problems with it.

Some months later I was discussing all the meds I was on with my Rheumatologist as I wanted to take as little as possible. I told him I never had reflux. Thank you GerriMc. That is reassuring.

Will update after the appointment. I should hope so - since PPIs increase the risk of cardiovascular disease quite considerably! I do wish they'd stop handing out things "just in case". I was prescribed Omeprazole when I started on pred to protect my stomach. I take Adcal too. I've never suffered with reflux. I'm going to reduce and come off Omeprazole and take my pred with a little yogurt and my daily porridge as I did this morning.

I was told to take the omeprazole 30 mins before food. Hi Janstr. With all the information received you might have to discuss with your GP if they are all required.

I have osteoporosis, so need the AA. Omeprazole is to stop stomach issues with the others. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. About Log in Join. Join Write.

Home About Posts Members. Hi everyone I hope you are all enjoying the lovely weather and progressing well with our common health issue. I decided to stop it 2 weeks ago as I am now only on 2 mgs of Prednisolone and will discuss with my Rheumatologist in 2 weeks My current concern now is Omeprazole.

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Mitziecat in reply to GCA 4 years ago. Two weeks separated the first doses of each study period. Eighteen volunteers entered the study; pharmacokinetic data were evaluable for 15 participants.

Headache was the most common drug-related AE. Rimmy mary EileenH mary Is Zantac an H2 inhibator? Michdonn amkoffee. Hi Mary I was prescribed Omeprazole. Michdonn mary Anhaga mary Michdonn Anhaga.

I am one been on Omeprazole for years now. I do not seem to have any problems with it, so far! EileenH Michdonn. Michdonn EileenH. Thanks, keep smiling! I have been on pred for a year and half, present dosage 6 mg. Recently, old ulcers, unknown to me, bled, caused by a blood thinner used duriing a knee replacement.

I was treated with two medications for a month beginningi in the hospital. A few months later, I was given mg Ranitidine 2 xs a day and developed hives after three pils. I was switched to 20 mg Omeprazole Prilosec 1 x a day for the remainder of the month. I have had a frequent sharp pain every few days in the general areaof my left side, not sure where. I stopped drinking wine with meals, changed to a low acid instant coffee and food diet, et al, to see if the pain would go away.

I am hoping the medication works. So far no pain for a few days. Thank you for your kind words. I forgot to mention that I also take Alendronate Sodium Tablets, started last year but stoppped for dental and knee operation for half a year. I just took my second weekly pill yesterday. Thank you for this devastating news. I had no idea.

Posted 5 years ago9 users are following. I was prescribed omeprazole Prilosec when a side effect of prednisone seemed to be an irritated stomach.

Now I am wondering if the prilosec is the cause of my irritated stomach and belly. Any thoughts? Any one else have the additional prescription of omeprazole? Posted 5 years ago. It is quite common for people to take a PPI like omeprazole or lansoprazole when on Prednisone as it can be helpful in protecting the stomach from irritation - and many doctors prescribe it for this as a matter of routine.

I have personally never had any side effects - especially of a worsening 'stomach' variety even from my usage over a long period. Hope you sort it out - it's not a good thing to have that kind of tummy whatever else is going on.

Omeprazole commonly causes gastric problems - which I assume you mean when you say "irritated stomach and belly". A more objective description would be helpful! It commonly causes abdominal painbloating, wind and diarrhoea which can be severe. One lady was unable to leave the house because of the need to be near a toilet. Many doctors prescribe a PPI the group of drugs of which omeprazole is a member when patients are on pred. I have never used it and neither have quite a few on the forums.

I was on gastro-resistant tablets for some time - only available in the UK - and otherwise used yoghurt like many of my friends. An alternative is ranitidine, sold OTC as Zantac, which does the same thing, suppressing acid production, but with a completely different mechanism and, as a result, different and fewer side effects. Yes, Zantac, ranitidine, is a H2 antagonists, also called H2 blockersare a class of medications that block the action of histamine at the histamine H2 receptors of the parietal cells in the stomach.

Good luck! I hope u feel better!! I was prescribed Omeprazole. Interesting to know if this has the same affect on others that you are experiencing. Maybe have a work with your GP. Good luck. Hi mary, I been taking Omeprazole for over 10 years and Predinisone now for about a year with no problems. I never had a problem with the Omeprazole, but the side effects of the Predinisone are tough.

I cannot imagine what it would be like to have PMR without Predinisone. If you look up omeprazole you will find that it was not intended as a longterm medication, although many people do seem to take it for years. It can add to the potential bone thibnning effects of prednisone, so if you don't need it, don't take it. What other things did you try to relieve the irritation of pred? Have you had a dexascan? Omeprazole can cause osteoporosis all on its own in some people.

There will always be people where it doesn't have that effect - but without a dexascan you can't know. Yes, EileenH two dexascans one about three years ago and one last fall before skiing. I been thinking of asking for one this year before skiing. My left hip was a little less dense, I guess that is how you say it! Hi peggy, I been on Omeprazole for about 14 years and Predinisone about a year with no problems.

Good luck on your journey. On my with a smile on my face! You are welcome peggy, mg should not of helped with the PMR. I tried it first. I could not live a normal life without Predinisone. Once again good luck on your journey. Smile on my face working my way down the road.

If you have a history of ulcers you should NOT have been put on alendronic acid - it is an explicit contraindication, particularly if it is in the last year or so, but I wouldn't accept being given it at all under the circumstances. Join this discussion or start a new one? We want the forums to be a useful resource for our users but it is important to remember that the forums are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters.

New discussion Reply. Rimmy mary EileenH mary Is Zantac an H2 inhibator? Michdonn amkoffee. Hi Mary I was prescribed Omeprazole. Michdonn mary Anhaga mary Michdonn Anhaga. I am one been on Omeprazole for years now. I do not seem to have any problems with it, so far! EileenH Michdonn. Michdonn EileenH. Thanks, keep smiling! I have been on pred for a year and half, present dosage 6 mg. Recently, old ulcers, unknown to me, bled, caused by a blood thinner used duriing a knee replacement.

I was treated with two medications for a month beginningi in the hospital. A few months later, I was given mg Ranitidine 2 xs a day and developed hives after three pils.

I was switched to 20 mg Omeprazole Prilosec 1 x a day for the remainder of the month. I have had a frequent sharp pain every few days in the general areaof my left side, not sure where. I stopped drinking wine with meals, changed to a low acid instant coffee and food diet, et al, to see if the pain would go away.

I just took my second weekly pill yesterday. Thank you for this devastating news. I had no idea. No dr. Contains personal information. Duplicate post. Offensive topic.

Delete request or other:. Notes on prednisone and omeprazole close.

No interactions were found between omeprazole and prednisolone. However, this does not necessarily mean no interactions exist. We recommend you take medication, such as omeprazole, before taking your steroids. This medication belongs to a group of drugs called proton pump inhibitors . We recommend you take medication, such as omeprazole, before taking your steroids. This medication belongs to a group of drugs called proton pump inhibitors . There is no reason why you can't stop omeprazole. The NICE recommendations are that patients taking Prednisolone should be offered a PPI and. LACK OF INTERACTION BETWEEN LANSOPRAZOLE OR OMEPRAZOLE AND PREDNISONE 8 of 16 participants taking lansoprazole (56%), 4 of. 17 of participants taking. Thank you for this devastating news. This medicine may cause hypomagnesemia low magnesium in the blood.

In a recently reported case, administration of omeprazole, a "proton pump" inhibitor, was temporally associated with the clinical relapse of pemphigus in a year-old woman whose condition had been stabilized with a fixed dose of prednisone, suggesting the possibility of a drug interaction.

This placebo-controlled, randomized, double-blind, three-period crossover study was conducted to evaluate and compare the pharmacokinetics of prednisolone after a single dose of prednisone given during multi-dose administration of lansoprazole or omeprazole. Lansoprazole 30 mg , omeprazole 40 mg , or placebo was administered once daily under fasted conditions for 7 days to healthy male volunteers. On the seventh day, a single dose of prednisone 40 mg was administered concomitantly with the study medication, and plasma prednisolone concentrations were measured by high-performance liquid chromatography for 24 hours thereafter.

Two weeks separated the first doses of each study period. Eighteen volunteers entered the study; pharmacokinetic data were evaluable for 15 participants. Headache was the most common drug-related AE.

No serious AEs were reported, and no subject withdrew from the study because of an AE. Concomitant administration of lansoprazole or omeprazole does not affect the absorption, biotransformation, or disposition of a single dose of prednisone. All three treatment regimens were well tolerated. Abstract In a recently reported case, administration of omeprazole, a "proton pump" inhibitor, was temporally associated with the clinical relapse of pemphigus in a year-old woman whose condition had been stabilized with a fixed dose of prednisone, suggesting the possibility of a drug interaction.

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