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- Topical tretinoin therapy and oral lichen planus



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We also use third-party cookies that help us analyze and understand how you use this website. These cookies will be stored in your browser only with your consent. You also have the option to opt-out of these cookies. But opting out of some of these cookies may affect your browsing experience. Biochemical studies included the use of antibodies anti-cytokeratins , anti-filaggrine for the immunohistochemical evaluation of keratinization and 2-dimensional gel electrophoresis for measuring cytokeratins.

In patients with lichen planus, histological changes during treatment showed that, in the 10 patients in the tretinoin group, keratinization disappeared in 6 and decreased significantly in 3. Immunohistochemistry revealed that cytokeratins and filaggrin disappeared in 57 p. Bidimensional gel electrophoresis showed that cytokeratins 1, 2, 10 and 11 disappeared only in the tretinoin group 60 p.

In patients with leukoplakia, histological changes during treatment showed that, in the tretinoin group, keratinization disappeared in 5 cases and decreased in 5 others.

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- Tretinoin for oral lichen planus



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Bidimensional gel electrophoresis showed that cytokeratins 1, 2, 10 and 11 disappeared only in the tretinoin group 60 p. In patients with leukoplakia, histological changes during treatment showed that, in the tretinoin group, keratinization disappeared in 5 cases and decreased in 5 others. Immunohistochemistry revealed that cytokeratins disappeared in 30 p. Bidimensional electrophoresis demonstrated that cytokeratins 1, 2, 10 and 11 disappeared in 43 p.

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topical tretinoin is clinically effective and well tolerated compared with placebo for the treatment of oral leukoplakia and oral keratosic or erythematous. Background: Treatment of oral lichen planus (OLP) is a major challenge for et al: Topical tretinoin therapy and oral lichen planus. February 5, ; Lichen Planus Severity Index: A new, valid scoring system to March 1, ; Clinical and pathological characterization of oral mucosal. Topical tretinoin > or = % improved the appearance of mild-to-severe photodamage. Tazarotene % and isotretinoin % provided. The treatment of severe forms of oral lichen planus is still relatively unsatisfactory. In this controlled study, % tretinoin in an adhesive base was. Necessary cookies are absolutely essential for the website to function properly. Abstracts from current literature.

In earlier work, we demonstrated that 0. Here we aimed to complete this clinical protocol with histological and biochemical analyses comparing the biopsy specimens collected at inclusion and those collected after 4 months of treatment.

Histological results were based on changes in keratinization observed between onset of treatment and 4 months treatment. Biochemical studies included the use of antibodies anti-cytokeratins , anti-filaggrine for the immunohistochemical evaluation of keratinization and 2-dimensional gel electrophoresis for measuring cytokeratins.

In patients with lichen planus, histological changes during treatment showed that, in the 10 patients in the tretinoin group, keratinization disappeared in 6 and decreased significantly in 3.

Immunohistochemistry revealed that cytokeratins and filaggrin disappeared in 57 p. Bidimensional gel electrophoresis showed that cytokeratins 1, 2, 10 and 11 disappeared only in the tretinoin group 60 p. In patients with leukoplakia, histological changes during treatment showed that, in the tretinoin group, keratinization disappeared in 5 cases and decreased in 5 others.

Immunohistochemistry revealed that cytokeratins disappeared in 30 p. Bidimensional electrophoresis demonstrated that cytokeratins 1, 2, 10 and 11 disappeared in 43 p.

Abstract In earlier work, we demonstrated that 0.



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