Prednisone Weight Gain: Causes and Prevention - Fluid retention and increased appetite are two side effects of this drug

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- Weight Gain: The Unwanted Side Effect of Prednisone for UC | Everyday Health



 

Over half of the prednisone users I surveyed stated that their 1 concern while taking prednisone is weight gain. This means a previously pound person gains pounds.

Doses of prednisone under 5 mg are unlikely to case weight gain. The longer time you take prednisone, the more likely you are to gain weight. Later, prednisone causes the opposite effect and makes fat cells enlarge. Taking prednisone less than seven days does not have much of an impact on body weight. Long-term therapy causes significant weight gain. Your face swells into a round shape like the moon as the dose goes up. This means that at low doses, moon face is uncommon.

Moon face slowly goes away as you slowly taper off prednisone. Within two weeks or so of stopping prednisone, most people report that moon face has completely disappeared. Moon face is one of the ways that prednisone redistributes fat :. Prednisone looks almost identical to cortisol, so the body is tricked into thinking they are the same.

Also, enzymes break down the prednisone so that it becomes even more similar to cortisol. Your body does whatever it can to give you that energy in the form of blood sugar. The liver releases sugar. Fat cells block the uptake of sugar.

All this sugar allows your muscles to work fast to escape or fight back. The problem is, when we are on prednisone, the tiger never goes away. The energy storage hormone, insulin, sees this extra energy and signals the body to store the high blood sugar as fat.

Appetite Stimulation. High insulin makes us feel hungry. Prednisone hijacks normal signals in your metabolism to keep your weight normal. For example, leptin is the fullness hormone released by fat cells. Leptin tells you that you feel full and can stop eating.

Somehow prednisone blocks the signals of leptin, so your normal feeling of hunger is missing. You can eat junk food until your stomach hurts in fullness, but you may not reach a point that you feel full.

Having too high levels of leptin leads to leptin resistancesimilar to insulin resistancewhere even high levels no longer do the job. This leads to fat storage as well. Prednisone breaks down bones, leading to bone loss and possibly osteoporosis. Prednisone also breaks down muscles, both of which lead to skinnier arms and legs despite a rounding belly and face. The percent of lean body mass determines your resting metabolic rate which is the amount of calories you use while at rest.

Since the lean body mass is going down, the amount of calories you normally use while sitting goes down. Retain Salt. Prednisone affects the salt balance of the body. Normally your kidneys keep a steady salt balance of sodium and potassium, which are opposites inside the body. Potassium is high inside cells, while sodium is high outside cells.

Prednisone causes the kidneys to hold onto the sodium, which leads to potassium loss. High sodium causes bloating, water retentionand contributes to moon face. Mood Changes. For example, maybe you can normally tolerate someone cutting you off on the freeway. But on prednisone, your reaction is heightened, quicker, and possibly less reasonable. In scientific speak, there is less space for your prefrontal cortex to modulate your reaction.

Prednisone mood changes can possibly lead to less will power to deal with food, because you are using up all your will power to keep a steady mood. Personality changes can lead to less ability to resist binges. This means starving yourself is not a good idea while on prednisone.

Sleep Changes. Prednisone use can lead to the 1 tweeted side effectinsomnia. Sleep is a very important time for keeping a regular metabolism. Fewer hormones released during sleep leads to fat storage. Less sleep leads to less will power to resist temptations. Now that you understand how prednisone causes weight gain, you have the information you need to know which strategies could work and which do not work to keep off the weight.

Focusing on eating high quality food low in refined sugar is the foundation of preventing prednisone weight gain. Use the prednisone appetite to eat foods rich in nutrients. Improving your sleep and exercising enough, but not too much, can also help keep off the pounds. The goal while taking prednisone should be to slow down or stop the weight gain, and not worry about losing weight.

Megan is here to help guide you through this process. Megan created a supplement designed especially for people taking prednisone. You are being redirected to our trusted and authorized Nutranize product website.

The Nutranize website is designed, constructed and endorsed by Dr. Megan Milne, the Prednisone Pharmacist. Please grant us just a few seconds to get you there.

Watch the video or enjoy reading further below. Does prednisone make you gain weight? Weight gain is one of the most common side effects of prednisone. How much weight is common? When do I gain weight? How long does it take? Will I gain weight if I only take prednisone short-term?

Moon face is one of the ways that prednisone redistributes fat : Moon Face: round face Buffalo Hump: fat on shoulder and neck area Belly Fat: even a man can look pregnant How does prednisone cause weight gain? High blood sugar leads to Fat The energy storage hormone, insulin, sees this extra energy and signals the body to store the high blood sugar as fat. Liver goes into energy production mode and makes sugar Fat cells store extra sugar as fat Kidney pees extra sugar Appetite Stimulation High insulin makes us feel hungry.

Prednisone Changes Metabolism Prednisone hijacks normal signals in your metabolism to keep your weight normal. Retain Salt Prednisone affects the salt balance of the body. Sleep Changes Prednisone use can lead to the 1 tweeted side effectinsomnia. So am I doomed? Is prednisone making you miserable, too? Find Replenishment Dr.

Things are When to take Calcium with Thyroid Medicine? Can Prednisone Affect your Thyroid? Can prednisone affect your thyroid? Yes, prednisone can affect your thyroid. You are being taken to my store.

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Prednisone and Weight Loss — Foundation for Sarcoidosis Research



 

Prednisone affects the salt balance of the body. Normally your kidneys keep a steady salt balance of sodium and potassium, which are opposites inside the body. Potassium is high inside cells, while sodium is high outside cells. Prednisone causes the kidneys to hold onto the sodium, which leads to potassium loss.

High sodium causes bloating, water retention , and contributes to moon face. Mood Changes. For example, maybe you can normally tolerate someone cutting you off on the freeway. But on prednisone, your reaction is heightened, quicker, and possibly less reasonable.

In scientific speak, there is less space for your prefrontal cortex to modulate your reaction. Prednisone mood changes can possibly lead to less will power to deal with food, because you are using up all your will power to keep a steady mood. Personality changes can lead to less ability to resist binges.

This means starving yourself is not a good idea while on prednisone. Sleep Changes. Prednisone use can lead to the 1 tweeted side effect , insomnia.

Sleep is a very important time for keeping a regular metabolism. Fewer hormones released during sleep leads to fat storage.

Less sleep leads to less will power to resist temptations. Now that you understand how prednisone causes weight gain, you have the information you need to know which strategies could work and which do not work to keep off the weight. Focusing on eating high quality food low in refined sugar is the foundation of preventing prednisone weight gain. Use the prednisone appetite to eat foods rich in nutrients. Improving your sleep and exercising enough, but not too much, can also help keep off the pounds.

The goal while taking prednisone should be to slow down or stop the weight gain, and not worry about losing weight. Megan is here to help guide you through this process. Megan created a supplement designed especially for people taking prednisone. You are being redirected to our trusted and authorized Nutranize product website. The Nutranize website is designed, constructed and endorsed by Dr.

Megan Milne, the Prednisone Pharmacist. Please grant us just a few seconds to get you there. Lupus Foundation of America. Finding the treatment approach for you. ILD nutrition manual: Prednisone and weight gain.

By Amber J. Tresca Amber J. Tresca is a freelance writer and speaker who covers digestive conditions, including IBD. She was diagnosed with ulcerative colitis at age Digestive Health. Inflammatory Bowel Disease. Amber J. Learn about our editorial process.

Medically reviewed Verywell Health articles are reviewed by board-certified physicians and healthcare professionals. These medical reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research.

Content is reviewed before publication and upon substantial updates. Learn more. Learn about our Medical Expert Board. Table of Contents View All. Table of Contents. Why It's Used. How to Lose Weight. Frequently Asked Questions. Prednisone Frequently Asked Questions. IBD Weight Loss Prednisone weight gain is sometimes a desirable effect, as it can help reverse some unintended weight loss due to IBD or other conditions that reduce the appetite.

Prednisone Side Effects and Resources. Healthy Lifestyle Fad diet plans and pills promise quick weight loss, but a healthy lifestyle is the best way to lose weight. Frequently Asked Questions How long does it take to lose weight caused by prednisone? Does prednisone make you retain water? Learn More: What Is Edema? Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

See Our Editorial Process. Meet Our Medical Expert Board. Share Feedback. Was this page helpful? Additional reporting by Jordan M. Health Conditions A-Z. Health Tools. See All. DailyOM Courses. Ulcerative Colitis. Reviewed: May 10, Medically Reviewed. But prednisone comes with a range of unwelcome side effects, one of which is weight gain. How to Control Weight Gain on Prednisone If weight gain is particularly bothersome, talk to your doctor about modifying your drug regimen.

Minimize canned and processed foods , soy sauce, cold cuts, chips, and other salty snacks, because high-sodium foods contribute to water retention.

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- Avoid weight gain while on prednisone



    Yes, prednisone can affect your thyroid. Personality changes can lead to less ability to resist binges. Prednisone hijacks normal signals in your metabolism to keep your weight normal.

Reviewed: May 10, Medically Reviewed. But prednisone comes with a range of unwelcome side effects, one of which is weight gain. How to Control Weight Gain on Prednisone If weight gain is particularly bothersome, talk to your doctor about modifying your drug regimen. Minimize canned and processed foods , soy sauce, cold cuts, chips, and other salty snacks, because high-sodium foods contribute to water retention.

Choose low-calorie sources of calcium. Another prednisone side effect is the risk for bone mineral loss, so boosting calcium intake is important. Some, like whole milk, also contain a lot of fat. Instead, try lower-calorie sources of calcium, like low-fat dairy, broccoli, kale , and chia seeds , says Scarlata, and consider a supplement.

Consume more potassium. Increased potassium intake can combat water retention, notes Bedford. Good sources of this important mineral include oranges, grapefruit, bananas, kiwifruit, spinach, collard greens, and tomatoes. Opt for healthy fats. Small portions of healthy fats boost nutrition and help control hunger between meals.

Stick with a schedule. For this reason, you should try to eat regularly-timed meals, she says. Slow, steady loss gives you the best chance of keeping the weight off. Water retention, increased appetite, and decreased physical activity contribute to weight gain while taking prednisone. You may be able to prevent weight gain by eating a low-sodium, low-calorie diet and being physically active every day. Talk to your doctor about your fitness plan and ask them if a physical therapist may be right for you.

Not everyone gains a lot of weight while taking prednisone, but most people gain some. The increases should stop once you're on a lower dosage or off the drug.

Then you can focus on a healthy lifestyle that'll help you shed the extra pounds. The best way to proceed when you're on prednisone is to focus first and foremost on getting better. A healthy lifestyle is likely beneficial for that, too. If prednisone does lead to added body fat, it'll be easier to tackle losing it when your symptoms are less of a burden.

Fortunately for most people, as prednisone is tapered and stopped, the weight gain will stop and reverse. However, since everyone is different, it is difficult to say how long it will take to achieve prednisone weight loss.

Yes, fluid retention on prednisone is common. That's because prednisone can cause you to hold onto salt and lose potassium. National Institutes of Health, U. National Library of Medicine: MedlinePlus. John Hopkins Medicine. Safety of low dose glucocorticoid treatment in rheumatoid arthritis: published evidence and prospective trial data. Ann Rheum Dis. J Physiol Lond. Dietary sodium and health: more than just blood pressure.

J Am Coll Cardiol. A practical guide to the monitoring and management of the complications of systemic corticosteroid therapy. Allergy Asthma Clin Immunol. Lupus Foundation of America. Finding the treatment approach for you. ILD nutrition manual: Prednisone and weight gain. By Amber J. Tresca Amber J. Tresca is a freelance writer and speaker who covers digestive conditions, including IBD.

She was diagnosed with ulcerative colitis at age Digestive Health. Inflammatory Bowel Disease. Amber J. Learn about our editorial process. Medically reviewed Verywell Health articles are reviewed by board-certified physicians and healthcare professionals.

These medical reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Content is reviewed before publication and upon substantial updates. Learn more. Learn about our Medical Expert Board.

Table of Contents View All. Table of Contents. Why It's Used. How to Lose Weight. Frequently Asked Questions. Prednisone Frequently Asked Questions. IBD Weight Loss Prednisone weight gain is sometimes a desirable effect, as it can help reverse some unintended weight loss due to IBD or other conditions that reduce the appetite.

Prednisone Side Effects and Resources. Healthy Lifestyle Fad diet plans and pills promise quick weight loss, but a healthy lifestyle is the best way to lose weight. Frequently Asked Questions How long does it take to lose weight caused by prednisone? Does prednisone make you retain water? Learn More: What Is Edema?

He is the vice chair for ambulatory services for the department of medicine at Weill Cornell Medical College in New York, where he is also a professor. He was the founding editor and co-editor in chief of Inflammatory Bowel Diseases.

Healthcare providers use steroids to treat many inflammatory conditions, including inflammatory bowel disease IBD and autoimmune disorders. Weight gain is a common side effect of prednisone.

That may be welcome if you're underweight because of your medical condition. But if you're at a healthy weight or you're already overweight, it's likely unwelcome. This article looks at why prednisone causes weight gain, how you can limit the amount you gain, and how to lose it once you're off of prednisone or on a lower dosage.

Prednisone is a synthetic steroid similar to the natural stress hormone cortisolwhich plays important roles in your body. Cortisol helps regulate:. Cortisol is produced by your adrenal glands —a pair of triangular glands located above the kidneys. Like cortisol, prednisone lowers inflammation and suppresses the immune system. It may be prescribed to help manage conditions that involve inflammation and abnormal immune function, such as:.

Prednisone can work fast. Because of that, it's often used to get a condition under control until a more sustainable, long-term treatment plan starts working. Prednisone should be used for as short a time as possible. Then, when your inflammation subsides, your doctor may gradually lower your dose. A drawback of prednisone is that it can make you gain a lot of weight. The higher the dose and the longer you take it, the more weight you're likely to put on.

For most people, that was less than 10 pounds. Prednisone causes weight gain for several reasons, including:. Prednisone weight gain is sometimes a desirable effect, as it can help reverse some unintended weight loss due to IBD or other conditions that reduce the appetite.

Weight gain attributed to prednisone use may actually be due to reduced physical activity. This isn't due to prednisone itself—it's due to many of the conditions it's used to treat. Symptoms such as pain and fatigue can lead people to be less active. Understanding why prednisone weight gain happens means you can take steps to avoid it. You may be able to prevent prednisone weight gain by:.

Eating a reduced-sodium diet and increasing potassium can help you avoid or lose extra water weight. You can meet these nutrition goals by:. It can be tricky to avoid gaining weight when prednisone gives you a bigger appetite.

To avoid gaining weight, try the following:. Regular exercise can also help prevent or lessen weight gain from prednisone. Talk to your doctor about starting a physical activity routine. Your activities may need to be tailored to your symptoms and condition s.

Try to find something that can help you lose weight now and is sustainable for the long term. When you have an underlying chronic illness, a tailored exercise program is important. Therefore, getting a referral to a physical therapist may be helpful. That makes it easier to approach weight loss. Any body fat you gained on prednisone won't automatically go away. As with any weight loss, it may help to have a healthful eating plan and get regular exercise.

If prednisone was effective and your health condition is under control, it'll be easier to eat well and be active again. Check with your healthcare provider on what types of diet and exercise are appropriate for you. If you have trouble taking off the weight, you may want to see a nutritionist for help with a healthy diet plan. Fad diet plans and pills promise quick weight loss, but a healthy lifestyle is the best way to lose weight.

Slow, steady loss gives you the best chance of keeping the weight off. Water retention, increased appetite, and decreased physical activity contribute to weight gain while taking prednisone. You may be able to prevent weight gain by eating a low-sodium, low-calorie diet and being physically active every day.

Talk to your doctor about your fitness plan and ask them if a physical therapist may be right for you. Not everyone gains a lot of weight while taking prednisone, but most people gain some. The increases should stop once you're on a lower dosage or off the drug. Then you can focus on a healthy lifestyle that'll help you shed the extra pounds.

The best way to proceed when you're on prednisone is to focus first and foremost on getting better. A healthy lifestyle is likely beneficial for that, too. If prednisone does lead to added body fat, it'll be easier to tackle losing it when your symptoms are less of a burden. Fortunately for most people, as prednisone is tapered and stopped, the weight gain will stop and reverse.

However, since everyone is different, it is difficult to say how long it will take to achieve prednisone weight loss. Yes, fluid retention on prednisone is common.

That's because prednisone can cause you to hold onto salt and lose potassium. National Institutes of Health, U. National Library of Medicine: MedlinePlus. John Hopkins Medicine. Safety of low dose glucocorticoid treatment in rheumatoid arthritis: published evidence and prospective trial data. Ann Rheum Dis. J Physiol Lond. Dietary sodium and health: more than just blood pressure. J Am Coll Cardiol.

A practical guide to the monitoring and management of the complications of systemic corticosteroid therapy. Allergy Asthma Clin Immunol. Lupus Foundation of America. Finding the treatment approach for you. ILD nutrition manual: Prednisone and weight gain. By Amber J. Tresca Amber J. Tresca is a freelance writer and speaker who covers digestive conditions, including IBD.

She was diagnosed with ulcerative colitis at age Digestive Health. Inflammatory Bowel Disease. Amber J. Learn about our editorial process. Medically reviewed Verywell Health articles are reviewed by board-certified physicians and healthcare professionals. These medical reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Content is reviewed before publication and upon substantial updates. Learn more. Learn about our Medical Expert Board.

Table of Contents View All. Table of Contents. Why It's Used. How to Lose Weight. Frequently Asked Questions. Prednisone Frequently Asked Questions. IBD Weight Loss Prednisone weight gain is sometimes a desirable effect, as it can help reverse some unintended weight loss due to IBD or other conditions that reduce the appetite. Prednisone Side Effects and Resources. Healthy Lifestyle Fad diet plans and pills promise quick weight loss, but a healthy lifestyle is the best way to lose weight.

Frequently Asked Questions How long does it take to lose weight caused by prednisone? Does prednisone make you retain water? Learn More: What Is Edema? Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

See Our Editorial Process. Meet Our Medical Expert Board.

localhost › GoodRx Health › Drugs › Prednisone. Reduce sodium intake. Minimize canned and processed foods, soy sauce, cold cuts, chips, and other. Reduce sodium intake. Minimize canned and processed foods, soy sauce, cold cuts, chips, and other. It can be tricky to avoid gaining weight when prednisone gives you a bigger appetite. To avoid gaining weight, try the following Focusing on eating high quality food low in refined sugar is the foundation of preventing prednisone weight gain. Use the prednisone appetite to eat foods rich. Safety of low dose glucocorticoid treatment in rheumatoid arthritis: published evidence and prospective trial data. Bedford says the drug also causes fluid retentionwhich leads to swelling, often of the hands, legs, and feet, along with the face. Prednisone should be used for as short a time as possible. Share Feedback. As with any weight loss, it may help to have a healthful eating plan and get regular exercise.

Dealing with weight gain cause by prednisone is hard, here are some diet and exercise tip help combat this side-effect. Sleep problems, increased appetite, headaches, dizziness, nausea, bloating, and weight gain; all of these are symptoms that many sarc warriors have experienced while on prednisone. Since prednisone, a corticosteroid, is able to suppress inflammation leading to improved symptoms and possible prevention of permanent organ damage, despite side-effects, it remains a first line treatment for sarcoidosis.

For many patients, the one side effects that causes the most discomfort is weight gain. Weight gain from prednisone is usually caused by water retention and an increased appetite. Some people also experience body fat redistribution, a symptom that is characterized by fat deposits collecting in unusual areas like the base of the neck or back. Trying to figure out how to deal with rapid weight gain can seem overwhelming at times, but there are a few things you can do limit weight gain from prednisone and slowly reverse the process.

FSR understand that not all diets and exercise routines are right for everyone. Any changes to your diet or exercise routine should be discussed and reviewed with your physician in advance. Gaining weight while on prednisone is commonly caused by fluid retention. One way to limit the amount of water you retain, is to eat a low sodium diet. Sodium binds to water inside of the body and helps maintain the balance of fluid inside and outside of cells.

When you have a diet high in sodium, your using the extra salt to also hold on to extra water causing fluid retention. The University of San Francisco Medical Center recommends keeping your daily intake below 2, milligrams. Another way to control fluid retention is to make sure you eat enough potassium rich foods , about 4, milligrams daily.

Potassium helps to decrease sodium levels and also increases urine production which helps flush out extra fluids. Lean protein can also help promote weigh loss for patients on prednisone. Last, it is always important to make sure you are drinking the recommended about of water every day, about Drinking water is a great way to help you feel full and can help prevent over eating. Drinking water also can help flush unwanted toxins from your body.

While you are making your diet more prednisone-friendly, you can slowly begin to exercise. To begin, pick an easy activity that does not put too much stress on your body. Check out some sarc-inspired yoga tips if you need a starting point! Sarcoidosis, like many chronic diseases, wears down your psyche. Walking is an exercise that nearly anyone can do. Start with feet the first day. The key is movement instead of sitting. Finding a workout buddy can also help keep you motivated- sarc warrior Gretchen found that by teaming up with her friend to start working out, she had more confidence and accountability.

Not to mention, it also makes exercising more fun! Once you have decided on an exercise, follow the chart below, remembering to only increase the level when you feel comfortable. Always talk to your doctor before starting a new exercise regimen.

If you want to explore alternative medications other than prednisone, try sharing our FSR Treatment Guide with your physician. Created by our Scientific Advisory Board , this protocol details numerous medications that can be prescribed for sarc, including off-label therapies. A lot of doctors find resource this useful for choosing a treatment method other than long-term use of steroids like prednisone.

Wellness Prednisone and Weight Loss Dealing with weight gain cause by prednisone is hard, here are some diet and exercise tip help combat this side-effect. September 17, Prednisone Friendly Diet Gaining weight while on prednisone is commonly caused by fluid retention. Tips for a Low Sodium Diet. High Potassium Foods. Exercise Tips While you are making your diet more prednisone-friendly, you can slowly begin to exercise.

Read more about treatment options. Join the FSR Community to learn more and stay up to date on all things sarcoidosis. Search for:.



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