Omeprazole and prednisone -
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Omeprazole and prednisonePrednisolone and Omeprazole: Hi everyone I hope you - PMRGCAuk - Description and Brand Names
Omeprazole (Oral Route) Precautions - Mayo Clinic
My personal experience does not concur. Being of a very cynical nature - maybe someone on the committee had undeclared interests in PPIs? It does happen. They aren't in fact. Thank you for the information and it has been very helpful. I have not had any major effects from taking it but have been on it for 13 months.
Don,t feel I now need it with low dose Prednisolone. I have Barretts syndrome and have been taking a PPI for years - I take my PPI and Prednisilone in the morning together with Ramipril for blood pressure and vit D, Glucosamine for knees , and a few other self prescribed supplements.
Am I doing it wrong? I also take mine in the morning so no you are not doing it wrong. You could try going without for a day However, I will try alternate days.
I have been taking Omeprazole for various reasons on and off for years, with no idea until recently about the risk of osteoporosis. I am sitting in the GP waiting room right now awaiting a consultation on this very matter. Have taken Omeprazole and Lansoprazole before but both eventually upset my stomach have been PMR case for 5years Thro' these learned fellow sufferers, I have taken thick unsweetened Greek yoghurt instead and so far so good -for a long time.
I have a cup of tea. Breakfast varies -weekdays- cereals usually with a little more yogurt. Fri- boiled egg on toast ,Sat-fried egg and toast, Sun - almond croissant. Thank you for your reply. I have porridge and yogurts as part of my diet so will use as a replacement for Omeprazole.
I can't take porridge or cereals or bread cause of my type 2 diabetes. I used to hate yoghurt but have force fed myself in order to like it - so I take a small tub of greek style yoghurt and a boiled egg in the morning with my tablets. On discharge from hospital in is was given Lansoprazole 15mgs, to be taken half to one hour before the preds and aspirin. I have thick porridge before taking the preds every morning and have so far been fine without the PPI.
After a Dexa scan and being given incorrect results from such I refused to take Alendronic Acid, I was given a death threat for refusing to take them. Alarms bells rang when I checked the results on a web site which I could understand. My results indicated Osteopenia. They got my height wrong, I was shocked to see that I had lost three inches in height so I measured it myself and I have lost just about an inch in height.
They also got the BMI wrong. Hi again Mitziecat. So, saw GP. She dictated the referral while I was there and said it would take about 3 months. Asked me what PMR symptoms I have. Checked for scalp tenderness and asked about headaches, blurred vision etc. She was happy to leave my tapering pred to me and given me a load of blood test forms to check everything is on and repeat again in 3 months.
Did she check your calcium and vit D levels? No bisphosphonate of any sort without - if they aren't right it is a waste of time Hi PMRpro. Thanks for keeping an eye on that. Thank you Nerak12 for your reply. It is a worry about the long term impact on the bones and crumbling spines etc.
We have to make our own informed choices after researching natural alternatives or finding out the state of our bones in the process. As far as Omeprazole was concerned, rather than it protecting my stomach, it caused stomach problems so was consigned to the bin after a few days.
Likewise with Lansoprazole. Instead, I ate a 'live' probiotic yoghurt each day before taking Pred. As you are now on such a very low dose of Pred, as long as your bones are in good condition now, then you have done the right think in ditching the AA, BUT you should have had a DEXA scan done at the outset of steroid treatment so do get one done asap to find out the present state.
Thank you for the advice and you are quite right. Priority to get a scan done to know if I am at risk of osteoporosis. Reassuring to know that you have never needed it. I think diet can and exercise can play an important part. I so agree about diet and exercise - diet-wise I ate plenty of oily fish as well as calcium-rich food, and exercise-wise, once the PMRGCAUK symptoms were under sufficient control, I did Tai Chi and Nordic Walking, the latter being particularly helpful.
I read about the calcium and Vit D on this forum and phoned the GP and they were prescribed straight away - thanks to this forum. Not prescribing it for me was an oversight on the part of both my rheumy and GP who both admitted it - each apparently thought the other had put me on it! Being long before these PMR forums - or in fact the PMR Charities were around diagnosed over 15 years ago - I knew nothing about it at the time - so long live forums such as this! To be honest - I'm not sure how AA and omeprazole fit together anyway.
Omeprazole can lead to reduced bone density all on its own - because it interferes with the absorption of calcium. AA requires adequate calcium to be available to increase bone density. Did you have your calcium and vit D levels checked regularly? If you do decide to stop the omeprazole don't go cold turkey - it will lead to what is called rebound acid production.
Reduce the dose slowly - or switch to ranitidine Zantac instead which also reduces the acid production but seems a bit easier to stop. Many of us never took omeprazole for all sorts of reasons but took pred in the middle of a meal or with yoghurt.
I have had both calcium and vit D checked regularly and both reported to be OK. My calcium was high at the outset. I will taper off the omeprazole but unsure over what period of time. And then there is me. I have life-time Klinefelters Syndrome and have been on Omeprazole since because my body makes too much stomach acid. Osteoporosis is a side effect of Klinefelters because sorry about this bit my testes did not produce enough natural testosterone before I was born or before puberty to build my bones strong enough.
Osteoporosis started sometime before I reached puberty when the male changes should happen. I know this because two of my upper spinal discs fused together when I was 14 and I developed a curved spine. Klinefelters was diagnosed in when I was 46 , when Testosterone Replacement Therapy commenced and I had the changes that I'd missed around The osteoporosis stopped fracturing my ribs I'd had 7 rib fractures before diagnosis and I was at Osteopenia stage and the fractures stopped in I also have G.
The stomach acid had been investigated for many years by Heath Road Hospital doctors without them being able to work out what caused it. My G P at that time suspected that it was something genetic because I also had a very painful right breast.
Klinefelters sufferers get small breasts! She referred me to the Diabetes specialist at Heath Road who was also an Endocrinologist, and he took one look at my distorted facial features, very long legs and arms and compacted rib cage and said I think I know what's causing the problem but I have to do special blood tests to confirm the diagnosis.
I can make you feel better and stop the fractures but the treatment will go on for the rest of your life. There are a more horrors but I will stop there. So, I'd been on omeprazole for years before I started Prednisolone and have never had any problems. I'm on 8. Bear in mind that I am different to most of the male population, I just have had a similar combination of the same drugs that you are asking about. Thank you for your reply Colin. So sorry to hear about your diagnosis.
Sounds as though you have had a lot to contend with over the years. Looks like not everyone suffers long term effects. I just hate being on medication that I might not need, even if no problems with it.
Some months later I was discussing all the meds I was on with my Rheumatologist as I wanted to take as little as possible. I told him I never had reflux. Thank you GerriMc. That is reassuring. Will update after the appointment.
I should hope so - since PPIs increase the risk of cardiovascular disease quite considerably! I do wish they'd stop handing out things "just in case". I was prescribed Omeprazole when I started on pred to protect my stomach.
I take Adcal too. I've never suffered with reflux. I'm going to reduce and come off Omeprazole and take my pred with a little yogurt and my daily porridge as I did this morning. I was told to take the omeprazole 30 mins before food. Hi Janstr. Patient on two types of breath nine patients in the merck co.
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❾-50%}Omeprazole and prednisone. Prednisolone and Omeprazole: Hi everyone I hope you... - PMRGCAuk
Two weeks separated the first doses of each study period. Eighteen volunteers entered the study; pharmacokinetic data were evaluable for 15 participants. Headache was the most common drug-related AE.
No serious AEs were reported, and no subject withdrew from the study because of an AE. Concomitant administration of lansoprazole or omeprazole does not affect the absorption, biotransformation, or disposition of a single dose of prednisone.
My calcium was high at the outset. I will taper off the omeprazole but unsure over what period of time. And then there is me. I have life-time Klinefelters Syndrome and have been on Omeprazole since because my body makes too much stomach acid. Osteoporosis is a side effect of Klinefelters because sorry about this bit my testes did not produce enough natural testosterone before I was born or before puberty to build my bones strong enough. Osteoporosis started sometime before I reached puberty when the male changes should happen.
I know this because two of my upper spinal discs fused together when I was 14 and I developed a curved spine. Klinefelters was diagnosed in when I was 46 , when Testosterone Replacement Therapy commenced and I had the changes that I'd missed around The osteoporosis stopped fracturing my ribs I'd had 7 rib fractures before diagnosis and I was at Osteopenia stage and the fractures stopped in I also have G. The stomach acid had been investigated for many years by Heath Road Hospital doctors without them being able to work out what caused it.
My G P at that time suspected that it was something genetic because I also had a very painful right breast. Klinefelters sufferers get small breasts! She referred me to the Diabetes specialist at Heath Road who was also an Endocrinologist, and he took one look at my distorted facial features, very long legs and arms and compacted rib cage and said I think I know what's causing the problem but I have to do special blood tests to confirm the diagnosis.
I can make you feel better and stop the fractures but the treatment will go on for the rest of your life. There are a more horrors but I will stop there. So, I'd been on omeprazole for years before I started Prednisolone and have never had any problems. I'm on 8. Bear in mind that I am different to most of the male population, I just have had a similar combination of the same drugs that you are asking about.
Thank you for your reply Colin. So sorry to hear about your diagnosis. Sounds as though you have had a lot to contend with over the years. Looks like not everyone suffers long term effects.
I just hate being on medication that I might not need, even if no problems with it. Some months later I was discussing all the meds I was on with my Rheumatologist as I wanted to take as little as possible. I told him I never had reflux. Thank you GerriMc. That is reassuring. Will update after the appointment. I should hope so - since PPIs increase the risk of cardiovascular disease quite considerably! I do wish they'd stop handing out things "just in case".
I was prescribed Omeprazole when I started on pred to protect my stomach. I take Adcal too. I've never suffered with reflux. I'm going to reduce and come off Omeprazole and take my pred with a little yogurt and my daily porridge as I did this morning.
I was told to take the omeprazole 30 mins before food. Hi Janstr. With all the information received you might have to discuss with your GP if they are all required. I have osteoporosis, so need the AA. Omeprazole is to stop stomach issues with the others. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
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Join Write. Home About Posts Members. Hi everyone I hope you are all enjoying the lovely weather and progressing well with our common health issue. I decided to stop it 2 weeks ago as I am now only on 2 mgs of Prednisolone and will discuss with my Rheumatologist in 2 weeks My current concern now is Omeprazole. Positive thoughts and good wishes tomyou all. To view profiles and participate in discussions please join or log in.
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Not what you're looking for? Do most of you take Omeprazole as well as Prednisolone? I have been taking Omeprazole, a proton pump inhibitor, to protest my stomach lining from becoming Breathless and feeling off. PMR symptom? Also coated Prednisolone with omeprazole. Also after reading recent post about omeprazole with coated predisolene each morning, I am now I have taken it for the 3 years that I have been taking View more posts.
Related Posts. Omeprazole Is omeprazole necessary? Omeprazole When to stop taking Omeprazole? Contact us. CandyH Partner. Can anyone who has experienced it please explain the differe
Hi folks. I had a question. I started Prednisone a few weeks back and the doc prescribed me Omeprazole as well. When I take that stuff, I have the worst stomache issues ever, cramps, bloating, and more.
Do I NEED to take the omeprazole with the prednisone or can people take prednisone without the acid medication? Well I was put on Omeprazole for a while to deal with the horrible intense acid-reflux and heartburn i was getting from my dose of pred Because steroids in this case, prednisolone can cause gastritis, and several other stomach-related adverse effects, doctors often prescribe anti-acid medication such as Omeprazole alongwith.
Omeprazole, normally, does not cause the symptoms you report. It may even be prescribed to some patients that have these symptoms! You may not, individually, be 'tolerating' either the Omeprazole, the steroid, or any other medication you might have been prescribed alongwith.
I have taken steroids for anaphylaxsis and my son is on them for NS. I can tolerate high doses without reflux meds for atleast 2 weeks but he can't. I guess it is just an individual response. However if ur treatment plan requires you to take the steroids for a long period then I would advise that u stay on either Omeprazole or an alternative. Sorry to hear you're having trouble with those meds.
I take both of them every day and have never had a problem, other than that the prednisone ,makes my sugar go high, so I'm being weaned off it. However, that information will still be included in details such as numbers of replies. Oops, something went wrong. Join Inspire Create a Post. Taking omeprazole with Prednisone? Mrkewl98 Inactive. Sign in or join to bookmark. Thank you. React Sign in or join to react. Viewing as.
Sort by. This discussion has been closed to comments. Please start a new post. Dear Friend, Because steroids in this case, prednisolone can cause gastritis, and several other stomach-related adverse effects, doctors often prescribe anti-acid medication such as Omeprazole alongwith.
In your case: 1. You need to talk to your doctor again; ask for substitutes for Omeprazole. There are a few. Desianne Inactive. Delete Reply. Note Required.
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Concomitant administration of lansoprazole or omeprazole does not affect the absorption, biotransformation, or disposition of a single dose of prednisone. All. We recommend you take medication, such as omeprazole, before taking your steroids. This medication belongs to a group of drugs called proton pump inhibitors . Concomitant administration of lansoprazole or omeprazole does not affect the absorption, biotransformation, or disposition of a single dose of prednisone. All. There is no reason why you can't stop omeprazole. The NICE recommendations are that patients taking Prednisolone should be offered a PPI and AA. Concomitant administration of lansoprazole or omeprazole does not affect the absorption, biotrans- formation, or disposition of a single dose of prednisone. All. Check with your doctor immediately if you or your child has stomach cramps, bloated feeling, watery and severe diarrhea which may also be bloody sometimes, fever, nausea or vomiting, or unusual tiredness or weakness. I decided to stop it 2 weeks ago as I am now only on 2 mgs of Prednisolone and will discuss with my Rheumatologist in 2 weeks My current concern now is Omeprazole. I had a question.In a recently reported case, administration of omeprazole, a "proton pump" inhibitor, was temporally associated with the clinical relapse of pemphigus in a year-old woman whose condition had been stabilized with a fixed dose of prednisone, suggesting the possibility of a drug interaction.
This placebo-controlled, randomized, double-blind, three-period crossover study was conducted to evaluate and compare the pharmacokinetics of prednisolone after a single dose of prednisone given during multi-dose administration of lansoprazole or omeprazole. Lansoprazole 30 mg , omeprazole 40 mg , or placebo was administered once daily under fasted conditions for 7 days to healthy male volunteers. On the seventh day, a single dose of prednisone 40 mg was administered concomitantly with the study medication, and plasma prednisolone concentrations were measured by high-performance liquid chromatography for 24 hours thereafter.
Two weeks separated the first doses of each study period. Eighteen volunteers entered the study; pharmacokinetic data were evaluable for 15 participants. Headache was the most common drug-related AE. No serious AEs were reported, and no subject withdrew from the study because of an AE. Concomitant administration of lansoprazole or omeprazole does not affect the absorption, biotransformation, or disposition of a single dose of prednisone.
All three treatment regimens were well tolerated. Abstract In a recently reported case, administration of omeprazole, a "proton pump" inhibitor, was temporally associated with the clinical relapse of pemphigus in a year-old woman whose condition had been stabilized with a fixed dose of prednisone, suggesting the possibility of a drug interaction.

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